让黑色素瘤治疗更个性化:与凯伦·斯莫利博士在《黑色素瘤管理》杂志上的访谈。
Making melanoma therapy personal: an interview with Dr Keiran Smalley for Melanoma Management.
发表日期:2017 May
作者:
Keiran Sm Smalley
来源:
Lancet Gastroenterology & Hepatology
摘要:
Smalley博士于2001年在英国剑桥大学获得药理学博士学位。他曾在美国宾夕法尼亚州威斯塔研究院、伦敦大学学院肿瘤学系和癌症研究所富勒姆路从事博士后研究工作。目前,Smalley博士是弗罗里达莫菲特癌症中心肿瘤生物学和皮肤肿瘤科的教授,担任唐纳德·亚当慈善基金会黑色素瘤研究讲座和黑色素瘤和皮肤癌中心卓越主任。Smalley博士的实验室专注于开发针对黑色素瘤的靶向治疗策略,目前得到了国家癌症研究所、制药业和许多慈善机构的资助。迄今为止,Smalley博士在《癌症研究》、《癌症发现》、《癌症细胞》、《新英格兰医学杂志》、《国家科学院院刊》、《柳叶刀》、《胃肠病学》和《临床癌症研究》等顶尖同行评议期刊上发表了120多篇论文。他目前是《临床癌症研究》、《生化药理学》、《药品》,《黑色素瘤研究》和《美国临床皮肤科学杂志》的编委会成员,并担任《药理研究》的副编辑。 Smalley博士是国家癌症研究所/国立卫生研究院癌症治疗基本机理研究小组的创始成员,并曾在国防部、得克萨斯州和许多黑色素瘤研究基金会的同行评议小组中担任评审委员会成员。他还曾为宾夕法尼亚大学、匹兹堡大学和一些制药公司担任顾问角色。Smalley博士于2011年曾担任巴西圣保罗大学的客座教授,并于2014年获得了来自巴西政府的无国界科学奖学金。
Dr Smalley earned his PhD in Pharmacology from the University of Cambridge, UK, in 2001. He worked as a post-doctoral fellow in the Oncology Department of University College London, the Institute of Cancer Research, Fulham Road and the Wistar Institute, PA, USA. Currently, Dr Smalley is a Professor in the Departments of Tumor Biology and Cutaneous Oncology at the Moffitt Cancer Center, FL, USA. He is also currently the Donald A Adam Endowed Chair in Melanoma Research and is the Director of the Melanoma and Skin Cancers Center of Excellence. The lab of Dr Smalley focuses upon the development of targeted therapy strategies for melanoma and is currently funded by the NCI, the pharmaceutical industry and a number of philanthropic sources. Dr Smalley's work is highly translational in nature and work from his lab has led to the initiation of a number of clinical trials. To date, Dr Smalley has published over 120 papers in top peer-reviewed journals including Cancer Research, Cancer Discovery, Cancer Cell, New England Journal of Medicine, the Proceedings of the National Academy of Sciences, the Lancet, Gastroenterology and Clinical Cancer Research. He currently sits on the editorial boards of Clinical Cancer Research, Biochemical Pharmacology, Drugs, Melanoma Research and the American Journal of Clinical Dermatology and is the Associate Editor of Pharmacological Research. Dr Smalley is a charter member of the Basic Mechanisms of Cancer Therapeutics Study Section for the NCI/NIH and has served on many other peer review panels for the Department of Defense, the state of Texas and numerous melanoma research foundations. He has also fulfilled advisory roles with the University of Pennsylvania, the University of Pittsburgh and a number of pharmaceutical companies. Dr Smalley has been a visiting professor at the University of Sao Paulo, Brazil in 2011 and in 2014 received a Science Without Borders Scholarship from the Brazilian Government.