爱普斯坦－巴尔病毒（EBV）对结肠癌发展的影响的研究目前备受关注，特别是在讨论此病毒参与胃癌致癌机制的激烈讨论中。本综述旨在深入了解EBV对人体的影响过程，并关注病毒的生命周期、潜伏和裂解期以及可能检测到的蛋白质等问题。分析了报道EBV在结肠癌发展中的作用的论文，提供了总结表格，表明研究人群、样本数量、方法和结果。鉴于EBV影响的主要细胞是淋巴细胞，可以合理地假设该病毒参与了炎症性肠病的发展。回顾了相关的研究，证明病毒DNA存在于结肠炎症性疾病的组织中，包括微小和溃疡性结肠炎等。需要进行大规模研究以验证EBV对结肠癌发展的直接影响，应用各种检测病毒的方法并必须描述其定位。此外，还需要将这些数据与EBV的临床和形态学特征相对应。

The study of the influence of the Epstein-Barr virus (EBV) on the development of colorectal cancer is of current interest, particularly in light of the active discussion of the participation of this virus in the carcinogenesis of stomach cancer. In this review, aimed at a fundamental understanding of the processes associated with the impact of EBV on the human body, attention is paid to the issues of the life cycle of the virus, its phases (latent and lytic), as well as proteins that may be detected in each of the phases. The papers reporting on the role of EBV in the development of colorectal cancer have been analyzed. A summary table indicating the population under study, the number of samples, the method, and the result obtained is provided. Given that the primary cells affected by EBV are lymphocytes, it is logical to assume the involvement of this virus in the development of inflammatory bowel diseases. The review cites studies which confirm the presence of virus DNA in tissues in the inflammatory diseases of the colon, including microscopic and ulcerative colitis. To confirm the direct impact of EBV on the development of colorectal cancer, large studies with applying various methods for detecting the virus and the mandatory description of its localization are required. Besides, it is necessary to correlate these data with the clinical and morphological characteristics of EBV.