我们可以走多小？ 部分膀胱放射治疗和放射性种植治疗。
How Small Can We Go? Partial Bladder Radiation Therapy and Brachytherapy.
发表日期：2023 Jan
作者：
Jenna M Kahn, Geert A H J Smits, Bernard J Oosterveld, Elzbieta M van der Steen-Banasik
来源：
SEMINARS IN RADIATION ONCOLOGY
摘要：
肌肉侵袭性膀胱癌（MIBC）的器官保护可采用三种治疗法。包括经尿道切除术后进行放射治疗。放射增敏已成为MIBC的常规护理方法之一，具有较高的局部疾病控制和总体生存率。器官保护的目标是在保留功能良好的自然膀胱的同时治疗MIBC。对于如何最优化膀胱癌的放射治疗方法仍存在争议。在MIBC中，局部性膀胱部分切除已在较小的孤立性肿瘤中使用，并且具有足够的局部控制和良好的排尿功能。随着放射治疗技术的改进和现代化，通过使用成像技术和适应性放射治疗计划等技术，对部分膀胱进行较小的放射体积可能在逐渐发挥作用。在本文中，我们探讨了使用种植放射治疗和外加放射疗法部分膀胱区域在MIBC治疗中的应用。版权所有©2022 Elsevier Inc.。保留所有权利。
Organ preservation for muscle-invasive bladder cancer (MIBC) may use trimodality therapy. This includes transurethral resection followed by radiation therapy. Radiosensitization has become one of the standard of care approaches for MIBC with high rates of local disease control and overall survival. The goal of organ preservation is to treat MIBC while preserving a well-functioning natural bladder. Debate remains over the best way to optimize radiation therapy in bladder cancer. In MIBC the role of partial cystectomy has been utilized in smaller solitary tumors with adequate local control and good urinary function. As radiation therapy techniques improve and modernize, smaller radiation volumes to a partial bladder may play an increasing role as we utilize imaging techniques coupled with adaptive radiation therapy planning and other techniques such as brachytherapy. In this review, we explore the use of brachytherapy and partial bladder fields of external beam radiation therapy in the treatment of MIBC.Copyright © 2022 Elsevier Inc. All rights reserved.