随着黑素瘤遗传学阐明，新的概念应运而生。其中一个重要概念是“中间型”黑素瘤的识别，它们的遗传进展事件超出了黑素痣，但并不是完全恶性的。因此，黑素瘤存在一个遗传谱系，很可能对应生物行为。黑色素瘤发展有多条路径，具有不同的起始事件和特征性良性黑色素瘤，肿瘤的精确定位在这些路径上仍需建立并量化相应的进展风险。在本综述中，我将讨论基于临床、组织病理学和遗传特征的黑素痣分类，以及关于特定可识别亚型的黑色素瘤概念。版权所有 © 2022 皇家澳大利亚病理学院。由 Elsevier B.V. 发布。保留所有权利。

With the elucidation of the genetics of melanocytic tumours, new concepts have emerged. An important one is the identification of 'intermediate' melanocytic tumours, those with genetic progression events beyond those of melanocytic naevi but that are not fully malignant. Thus, melanocytic tumours exist on a genetic spectrum that likely corresponds to biological behaviour. There are multiple pathways to melanoma development with different initiating events and characteristic benign melanocytic neoplasms and the precise placement of tumours on these pathways remains to be established and the corresponding risks of progression quantified. In this review, I discuss the classification of melanocytic naevi based on clinical, histopathological and genetic features, as well as the concept of melanocytomas with discussion of specific recognisable subtypes.Copyright © 2022 Royal College of Pathologists of Australasia. Published by Elsevier B.V. All rights reserved.