近年来，研究表明磁性锚引导下的内镜黏膜下剥离术（MAG-ESD）是可行且安全的，可以促进所有难治性病变的治疗。然而，MAG-ESD的主要问题是无法在不撤回或重新插入内镜的情况下将磁性锚送入胃肠道。因此，我们的团队研发出一种可以通过活检通道轻松插入的磁性锚，以促进ESD牵张，然后评估其效果和安全性。该研究于2020年10月至2021年6月在中国哈尔滨医科大学附属第二医院进行。将接受ESD治疗的112名结肠肿瘤患者分为两组进行历史对照比较：放置磁性锚通道组（CPMAG组）和未使用辅助牵张的常规ESD对照组。比较两组之间的完整切除率、切除带肿瘤无残缺的侧/底边缘（R0切除）、剥离速度、手术时间、术中出血和穿孔并发症以及术后随访情况，以评估新磁性锚的临床效果和安全性。使用CPMAG-ESD的完整切除和R0切除率略高于常规ESD，但差异不具有统计学意义。使用CPMAG-ESD的中位数剥离速度高于常规ESD，但差异不具有统计学意义。使用CPMAG-ESD的术中出血和术后并发症少于常规ESD，但差异不具有统计学意义。使用CPMAG-ESD的中位数手术时间短于常规ESD（24.5分钟[范围：15.8-66.5分钟] vs39分钟[范围：29-58分钟]，p = 0.024），这种差异具有统计学意义。新的磁性锚引导下的ESD技术似乎是一种可行且安全的方法，可以用于治疗早期结直肠肿瘤的完整切除，提高黏膜下可视范围，降低不良事件。© 2023. Springer Nature Switzerland AG.

In recent years, studies have demonstrated that magnetic anchor-guided endoscopic submucosal dissection (MAG-ESD) is feasible and safe and may facilitate the treatment of all difficult lesions. However, the major problem with MAG-ESD is the inability to deliver the magnetic anchor to the gastrointestinal tract without withdrawal or reinsertion of the endoscope. Therefore, our team developed a magnetic anchor that could be easily inserted through the biopsy channel, facilitating ESD traction and evaluated its effectiveness and safety.The study was conducted between October 2020 and June 2021 at The Second Affiliated Hospital of Harbin Medical University, China. One hundred and twelve patients with colorectal tumors treated with ESD were divided into two groups for historical control comparison. A channel-placed magnetic anchor (CPMAG) group and a control group consisting of patients who had conventional ESD without adjuvant traction. The rate of en bloc resection and resection with tumor-free lateral/basal margins (R0 resection), dissection speeds, procedure time, intraoperative bleeding and perforation complications, and postoperative follow-up were compared between the two groups, so as to evaluate the clinical effect and safety of the new magnetic anchor.The en bloc resection and R0 resection rate with CPMAG-ESD were slightly higher than with conventional ESD but this was not statistically significant. The median dissection speeds with CPMAG-ESD were higher than with conventional ESD, but the difference was not statistically significant. Intraoperative bleeding and postoperative complications with the CPMAG-ESD were less than with conventional ESD, but this was not statistically significant. The median operating time was shorter with CPMAG- ESD than with conventional ESD (24.5 min [range 15.8-66.5 min] vs 39 min [range 29-58 min], p = 0.024), and this difference was statistically significant.The new magnetic anchor-guided ESD technique appears to be a feasible and safe method for treating early colorectal tumors with en bloc resection, with improvement of the submucosal visual field, and less adverse events.© 2023. Springer Nature Switzerland AG.