大多数患者在直肠癌切除手术后出现长期肠道功能障碍，被称为低位前切除综合征（LARS）。 LARS评分是为了评估丹麦患者的这种综合征及其对生活质量的影响而开发的。最近，英语和许多其他语言的版本已获得验证。本研究旨在验证LARS评分的土耳其翻译，以治疗直肠癌的患者为对象。 在三个土耳其中心于2000年5月至2018年5月间接受低位前切除手术的直肠癌患者接受了LARS评分问卷，欧洲研究与治疗癌症组织核心生活质量问卷[版本11]（EORTC QLQ-C30）和唯一的专门质量生活问题。随机选择的一部分患者在初始反应后2至4周内再次评估LARS评分以评估其测试-重测的可靠性。 总共审阅并联系了326名患者，其中222名（68％）符合分析标准（129名男性，93名女性，中位年龄64岁[范围：24-87岁，IQR = 14]）。 LARS评分和生活质量之间存在强烈的关联（p <0.01），测试-重测的可靠性很高。 整个研究组的组内相关系数为0.78（95％CI为0.73-0.83），亚组为0.79（95％CI为0.68-0.87），表明受试者间关联强。 土耳其LARS评分的心理测量特性与类似研究中先前发表的结果相似。 土耳其版LARS评分可视为衡量土耳其直肠癌患者LARS的有效且可靠的工具。 NCT05289531。© 2023. Springer Nature Switzerland AG.

Long-term bowel dysfunction after resection for rectal cancer, known as low anterior resection syndrome (LARS), is observed in many patients. The LARS score was developed to assess this syndrome and its impact on the quality of life in Danish patients. Recently versions in English and many other languages have been validated. The aim of this study was to validate the Turkish translation of the LARS score in patients who have undergone treatment for rectal cancer.Rectal cancer patients who underwent low anterior resection in May 2000- May 2018 in three Turkish centers received the LARS score questionnaire, the European Organisation for Research and Treatment Of Cancer Core Quality of Life questionnaire [Ed.11] (EORTC QLQ-C30), and a single ad hoc quality of life question. The test-retest reliability of the LARS score was evaluated by asking a randomly selected subgroup of patients to repeat the assessment of the LARS score 2 to 4 weeks after their initial response.A total of 326 patients were reviewed and contacted for the study, and 222 (68%) were eligible for the analyses (129 males, 93 females, median age 64 years [range:24-87 years, IQR = 14]) There was a strong association between the LARS score and quality of life (p < 0.01) and the test-retest reliability was high. The intraclass correlation coefficient was 0.78 (95% CI 0.73-0.83) for the whole study group and 0.79 (95% CI 0.68-0.87) for the subgroup, indicating strong reliability.The Turkish translation of the LARS score has psychometric properties comparable with previously published results in similar studies. The Turkish version of the LARS score can be considered a valid and reliable tool for measuring LARS in Turkish rectal cancer patients.NCT05289531.© 2023. Springer Nature Switzerland AG.