老年人中常见的良性黑素细胞和非黑素细胞皮肤肿瘤。格拉茨健康与老龄化研究(GSHA)的研究结果。
Common benign melanocytic and non-melanocytic skin tumors among the elderly. Results of the Graz Study on Health & Aging (GSHA).
发表日期:2023 Jan 19
作者:
Viktoria Gruber, Rainer Hofmann-Wellenhof, Peter Wolf, Elena Lucia Hofmann-Wellenhof, Helena Schmidt, Andrea Berghold, Andreas Wedrich
来源:
DERMATOLOGY
摘要:
良性皮肤肿瘤是最常见的皮肤发现,也是咨询皮肤科医生的主要原因之一。然而,不同身体部位的良性皮肤肿瘤的发病率以及它们与与阳光有关的行为的关系还没有得到充分的描述。我们旨在提高对健康优势的老年人口中最常见的良性皮肤肿瘤的解剖分布的了解。此外,我们还调查了与与太阳有关的习惯的关联。在Graz Study on Health&Aging(GSHA)队列中,共有100名参与者,其中37名男性和63名女性(平均年龄:67.2岁;范围:46-86岁)。肉眼观察了全身图像以寻找黑色素痣,脂溢性角化病,血管瘤,皮脂纤维瘤和黑斑。在调查表中收集了有关表型特征,阳光暴露,使用防晒措施和晒伤史的信息。常见的黑色素痣是最常见的皮肤病变。男性性别与腹部多个常见痣和非典型痣的存在有关。在青春期期间中欧纬度高的日照量与全身多个常见痣呈正相关。背部的多个常见痣和非典型痣与青春期和青年期分别频繁使用SPF防晒霜有关。我们的研究为考虑所有可见身体区域的最常见的良性皮肤肿瘤增加了新的知识。此研究可作为随后流行病学研究的参考基础。
Benign skin tumors are the most common skin findings and contribute to the major reasons for consulting a dermatologist. However, the frequency of benign skin tumors concerning different body areas and their relationship with sun-related behavior have not been sufficiently characterized. We aimed to improve knowledge about the anatomic distribution of the most frequently occurring benign skin tumors among a healthy predominant elderly population. Furthermore, we investigated associations with sun-related habits.In total, 100 participants, 37 men, and 63 women (mean age: 67.2 years; range: 46-86 years) were enrolled in the Graz Study on Health & Aging (GSHA) cohort. Full body images were investigated for melanocytic nevi, seborrheic keratoses, hemangiomas, dermatofibromas, and lentigines. Information on the phenotypic trait, sun exposure, use of sun-protective measures, and history of sunburns was collected in a questionnaire.Common melanocytic nevi were the most frequently encountered skin lesions. Male sex was associated with multiple common nevi on the abdomen and the presence of atypical nevi. High sun exposure in central European latitudes during adolescence was positively associated with multiple common nevi on the total body. Multiple common nevi and atypical nevi on the back correlated with frequent use of sunscreens with SPF during young adulthood and adolescence, respectively.Our study adds new knowledge about the most frequently occurring benign skin tumors, considering all visible body areas. This research may serve as a reference basis for following epidemiological studies.The Author(s). Published by S. Karger AG, Basel.