在过去的十年里，纳米医学在疾病的诊断和治疗方面经历了前所未有的发展。许多纳米医药已获得临床使用的批准，这表明了从实验室到床旁的纳米技术改进药物的临床转化的潜在价值。人工智能在纳米技术产品开发中的应用可能通过实现大数据集的获取和分析，并为癌症治疗调整精度纳米药物，从而改变医疗保健部门。AI支持的纳米技术可以提高患者的分子分析和早期诊断的准确性，并通过调整纳米药物的属性，实现有效的药物协同作用，降低纳米毒性，从而提高纳米药物的靶向性、个性化剂量和治疗效果。在这里，介绍了AI支持的纳米医药在癌症治疗方面的进展，并讨论了它们在诊断、监测、治疗以及精准医疗开发中的应用。版权所有©2023 Elsevier Ltd.。保留所有权利。

Over the last decade, the nanomedicine has experienced unprecedented development in diagnosis and management of diseases. A number of nanomedicines have been approved in clinical use, which has demonstrated the potential value of clinical transition of nanotechnology-modified medicines from bench to bedside. The application of artificial intelligence (AI) in development of nanotechnology-based products could transform the healthcare sector by realizing acquisition and analysis of large datasets, and tailoring precision nanomedicines for cancer management. AI-enabled nanotechnology could improve the accuracy of molecular profiling and early diagnosis of patients, and optimize the design pipeline of nanomedicines by tuning the properties of nanomedicines, achieving effective drug synergy, and decreasing the nanotoxicity, thereby, enhancing the targetability, personalized dosing and treatment potency of nanomedicines. Herein, the advances in AI-enabled nanomedicines in cancer management are elaborated and their application in diagnosis, monitoring and therapy as well in precision medicine development is discussed.Copyright © 2023 Elsevier Ltd. All rights reserved.