癌症是一个普遍存在、不断演变且极为重要的公共卫生问题。最近几十年新癌症病例数量急剧增加，使其成为全球贫困健康和死亡率最高的原因之一。虽然手术、放射和药物治疗等各种治疗策略已经发展成更为精密的方法，但癌症相关死亡人数并没有多少改善。因此，天然药物治疗发现被最近认为是一种替代方法。据估计，当今市场上前二十种药物中有三分之一是基于天然植物成分的。因此，主要的预防措施是全球癌症控制的重要组成部分。本篇综述提供了对天然膳食产品中生物活性成分作用机制的概述，这些成分可能有助于多种恶性肿瘤的预防和管理。 版权所有©2023 Elsevier B.V。

Cancer is a pervasive, constantly evolving, and significant public health concern. The number of new cancer cases has risen dramatically in the last decades, making it one of the top causes of poor health and mortality worldwide. Although various treatment strategies, including surgery, radiation, and pharmaceutical therapies, have evolved into more sophisticated, precise methods, there is not much improvement in the cancer-related death toll. Consequently, natural product-based therapeutic discoveries have recently been considered an alternative approach. According to an estimate, one-third of the top twenty medications in today's market have a natural plant-product-based origin. Accordingly, primary prevention is an essential component of worldwide cancer control. This review provides an overview of the mechanisms of action of bioactive ingredients in natural dietary products that may contribute to the prevention and management of multiple malignancies.Copyright © 2023 Elsevier B.V. All rights reserved.