乳头状肾癌是一种罕见的恶性肿瘤，晚期疾病的治疗选择有限。我们介绍一位62岁男性，患有左侧乳头状肾细胞癌的病例，接受了68Ga-FAPI (成纤维细胞激活蛋白抑制剂)-04和18F-FDG PET/CT成像检查。68Ga-FAPI-04 PET/CT显示所有18F-FDG PET/CT检测到的转移性病灶，包括多个淋巴结、骨和甲状腺，都具有不同程度的FAP表达。该病例突显了FAP靶向成像在乳头状肾癌的诊断和治疗监测中的潜在价值。 版权所有© 2023 Wolters Kluwer Health，Inc. 保留所有权利。

Papillary renal cell cancer is a rare malignancy with limited treatment options in the advanced stage of the disease. We present the case of a 62-year-old man with progressive left-sided papillary renal cell carcinoma who underwent 68Ga-FAPI (fibroblast activated protein inhibitor)-04 and 18F-FDG PET/CT imaging. 68Ga-FAPI-04 PET/CT demonstrated variable FAP expression in all metastatic lesions detected by 18F-FDG PET/CT, including multiple lymph nodes, bone, and thyroid. This case highlights that FAP-targeted imaging can be a promising modality for diagnostic and theranostic use in papillary renal cell carcinoma.Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.