研究动态
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使用DOTATATE PET区分镰切脑膜瘤和脑静脉窦血栓。

Differentiation of a Falcine Meningioma From Cerebral Venous Sinus Thrombosis Using DOTATATE PET.

发表日期:2023 Feb 07
作者: Isabelle Stetter, Jan-Michael Werner, Michael Schroeter, Claudia Baumann, Janina Neuneier, Marc Schlamann, Matthias Schmidt, Alexander Drzezga, Gereon R Fink, Norbert Galldiks
来源: CLINICAL NUCLEAR MEDICINE

摘要:

使用常规MRI区分脑肿瘤和非肿瘤性病变可能具有挑战性。临床症状通常保持不明确,MRI成像结果可能并不确切。我们介绍了一个23岁女性的病例,其MRI表明存在大脑静脉窦血栓形成。另一方面,额外的不典型MRI发现引发了对最初诊断的怀疑。考虑到需要具有更高敏感性和特异性的诊断程序来诊断肿瘤组织,使用标记放射性生长抑素受体配体DOTATATE(68Ga-DOTA-d-Phe1-Tyr3-octreotate)进行PET。DOTATATE PET有助于诊断枕叶脑膜瘤,与其在鉴别诊断中的价值相一致。版权所有©2023 Wolters Kluwer Health,Inc. 保留所有权利。
Differentiating brain tumors from nonneoplastic lesions using conventional MRI may be challenging. Clinical symptoms often remain unspecific, and imaging findings from MRI may be inconclusive. We present the case of a 23-year-old woman in whom an MRI suggested a cerebral venous sinus thrombosis. On the other hand, additional atypical MRI findings raised doubts regarding the initial diagnosis. Given the need for a diagnostic procedure with higher sensitivity and specificity for neoplastic tissue, PET with the radiolabeled somatostatin receptor ligand DOTATATE (68Ga-DOTA-d-Phe1-Tyr3-octreotate) was performed. DOTATATE PET facilitated the diagnosis of a falcine meningioma consistent with its value for the differential diagnosis of meningioma.Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.