在大型安全网医院接受放疗的被监禁者在癌症诊断阶段的不平等情况。
Inequalities in Cancer Stage at Diagnosis among Incarcerated Individuals Undergoing Radiation Therapy at a Large Safety Net Hospital.
发表日期:2023 Feb 07
作者:
Oluwadamilola T Oladeru, Christa M Lam, Muhammad M Qureshi, Ariel E Hirsch, Kimberley S Mak, Michael A Dyer, Minh Tam Truong
来源:
Int J Radiat Oncol
摘要:
在美国的监狱中,癌症是导致疾病相关死亡的主要原因,但我们缺乏关于监禁人群癌症治疗的数据。我们回顾性地研究了一家大型安全网医院接受放射治疗的被监禁个体的人口统计学和临床病理特征。在机构审查委员会批准后,我们确定了2003年1月至2019年5月期间接受放射治疗的80名被监禁患者。分析了患者特征、肿瘤类型和分期、治疗因素以及随访率的描述性统计数据。在研究期间,共有80人中的82个癌症诊断接受放射肿瘤学咨询。中位年龄为54岁(范围为46-64岁)。以白人、黑人和“其他”种族为主的患者分别占61.3%(n = 49)、28.8%(n = 23)和10%(n = 8)。大多数患者为男性(n = 75,93.8%)和英语使用者(n = 76,95%)。此外,50%(n = 40)有物质使用障碍史,75%(n = 60)有吸烟史。三种最常见的癌症类型分别为前列腺癌(n = 12,14.6%)、胃肠道癌(n = 14,17.1%)、胸部癌(n = 17,20.7%)和头颈癌(n = 21,25.6%)。肿瘤分期(AJCC)的分布为I期(n = 12,14.6%)、II期(n = 12,14.6%)、III期(n = 14,17.1%)、IV期(n = 38,46.3%)和未知/不可用(n = 6,7.3%)。在这个群体中,有65名患者接受了放射治疗,共66种癌症(80.5%)。其中,6个月、1年和5年的随访率分别为41.5%、27.7%和3.1%。限制分析仅限于I-III期患者(n = 30),显示了6个月、1年和5年的随访率分别为41.9%、22.6%和3.2%。这项研究突显了一种脆弱的患者群体在癌症诊断阶段的不平等,这些患者往往被排除在临床研究之外。大多数被监禁患者以III或IV期癌症就诊,即使是早期疾病的患者,随访率也很低。有必要采取措施了解和缓解被监禁患者的持续健康不平等。版权所有 © 2023 Elsevier Inc.
There is a dearth of data on cancer care in the incarcerated population, despite being the leading cause of illness-related death in United states' prisons. We retrospectively reviewed the demographic and clinicopathologic characteristics of incarcerated individuals who received radiation therapy at a large safety-net hospital.Following institutional review board approval, we identified 80 incarcerated patients who presented for radiation therapy between January 2003 and May 2019. Descriptive statistics on the patients, tumor types and stage, treatment factors, and follow-up rates were analyzed.80 individuals with 82 cancer diagnoses presented for radiation oncology consultation over the study period. The median age was 54 years (range, 46-64). Patients of White, Black, and "other" races comprised 61.3% (n=49), 28.8% (n=23), and 10% (n=8), respectively. Most patients were male (n=75, 93.8%) and English speakers (n=76, 95%). Moreover, 50% (n=40) had a substance use disorder history and 75% (n=60) had a smoking history. The three most common cancer types were prostate (n=12, 14.6%), gastrointestinal (n=14, 17.1%), thoracic (n=17, 20.7%), and head and neck (n=21, 25.6%). The distribution of tumor stage (AJCC) was I (n=12, 14.6%), II (n=12, 14.6%), III (n=14, 17.1%), IV (n=38, 46.3%), and unknown/unavailable (n=6, 7.3%). Of the cohort, 65 patients with 66 cancers (80.5%) received radiation. Among them, the 6-month, 1-year, and 5-year follow-up rates were 41.5%, 27.7%, and 3.1%, respectively. Subset analysis limited to stage I-III patients (n=30) revealed 6-month, 1-year and 5-year follow-up rates of 41.9%, 22.6%, and 3.2%, respectively.This study highlights inequalities in cancer stage at diagnosis among a vulnerable patient population that is largely excluded from clinical research. Majority of the incarcerated patients presented with stage III and IV cancers and have poor follow up rates even among those with early-stage disease. Efforts to understand and mitigate persistent health inequalities among incarcerated patients are warranted.Copyright © 2023. Published by Elsevier Inc.