研究动态
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脑器官样品恢复了大脑皮质损伤。

Brain organoids restore cortical damage.

发表日期:2023 Feb 03
作者: Nazlican Altinisik, Dhanasekaran Rathinam, Minh Tran, Jay Gopalakrishnan
来源: Cell Stem Cell

摘要:

大脑皮层的损伤是无法修复的,对再生医学构成挑战。关于脑器官能否代替受伤的脑区仍不清楚。在Cell Stem Cell杂志的这一期中,Jgamadze等人报告称,移植到大鼠视觉系统中的人类前脑器官长期保持结构连接,并在损伤后恢复了视觉功能。版权所有©2023 Elsevier Inc.发表。
Cortical damage is irreparable and poses a challenge to regenerative medicine. Whether brain organoids can compensate for injured brain regions remains unclear. In this issue of Cell Stem Cell, Jgamadze et al. report that human forebrain organoids transplanted into the rat visual system show long-term structural connectivity and the restoration of visual function following lesions.Copyright © 2023. Published by Elsevier Inc.