使用混合物点燃中性粒细胞的抗肿瘤免疫。
Firing up neutrophil anti-tumor immunity with cocktails.
发表日期:2023 Feb 13
作者:
Meiyi Li, Melissa Ng, Lai Guan Ng
来源:
CANCER CELL
摘要:
中性粒细胞是肿瘤中所有白细胞中占相当大比例的一类细胞,对促进肿瘤生长至关重要。在本期文章中,Linde等人证明由肿瘤坏死因子(TNF)、抗CD40单克隆抗体和结合肿瘤的抗体组成的抗体混合疗法可以提高中性粒细胞的抗肿瘤活性。版权所有©2023 Elsevier Inc.保留所有权利。
Neutrophils constitute a considerable proportion of all leukocytes found in tumors and are essential for promoting tumor growth. In this issue, Linde et al. demonstrate that an antibody cocktail therapy consisting of tumor necrosis factor (TNF), anti-CD40 monoclonal antibody, and tumor-binding antibody can boost the anti-tumor activity of neutrophils.Copyright © 2023 Elsevier Inc. All rights reserved.