研究动态
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68Ga-FAPI和18F-FDG PET/CT在骨上皮样血管内皮瘤评估中的对比。

68Ga-FAPI Versus 18F-FDG PET/CT in the Evaluation of Epithelioid Hemangioendothelioma of Bone.

发表日期:2023 Feb 17
作者: Weizhi Xu, Jiayu Cai, Tinghua Meng, YiZhen Pang, Haojun Chen
来源: CLINICAL NUCLEAR MEDICINE

摘要:

上皮样血管内皮瘤(EHE)是一种罕见的血管瘤,在骨骼中可能产生。这里我们介绍了一位62岁的疑似骨转移的男性患者,经过PET/CT检查以检测原发肿瘤。他接受了NCT04416165前瞻性试验下的18F-FDG和68Ga-FAPI PET/CT检查。在大多数骨病变中,68Ga-FAPI PET/CT的放射性示踪剂摄取率要比18F-FDG PET/CT高得多。没有观察到可能显示原发肿瘤的强烈摄取。随后的骨活检确诊了骨EHE病例。该病例提示68Ga-FAPI PET/CT可能是评估EHE的有用工具。版权所有©2023 Wolters Kluwer Health, Inc. 保留所有权利。
Epithelioid hemangioendothelioma (EHE) is a rare type of vascular tumor that may arise in bone. Here we presented a 62-year-old man with suspected bone metastases who underwent PET/CT to detect the primary tumor. He underwent 18F-FDG and 68Ga-FAPI PET/CT under the prospective trial NCT04416165. Radiotracer uptake was much higher with 68Ga-FAPI PET/CT than with 18F-FDG PET/CT in most of bone lesions. No intense uptake likely presenting the primary tumor was observed. Subsequent bone biopsy confirmed the diagnosis of EHE of bone. This case suggested that 68Ga-FAPI PET/CT might be a useful tool for evaluation of EHE.Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.