儿童B细胞急性淋巴细胞白血病罕见表现为广泛的骨髓外受累。一个七岁男孩被诊断为无痛性腮腺肿大。他患有全血细胞减少症和明显升高的乳酸脱氢酶。腮腺的细针穿刺细胞学提示是淋巴细胞性恶性肿瘤。流式细胞术和骨髓活检提示为B细胞急性淋巴细胞白血病。18F-FDG PET / CT显示广泛的骨髓疾病和脾脏，胰腺，肾脏，腮腺，颏下腺和泪腺的受累。他的脑功能代谢活动很低。版权所有©2023 Wolters Kluwer Health。保留所有权利。

Extensive extramedullary involvement as presentation is uncommon in pediatric B-cell acute lymphoblastic leukemia. A 7-year-old boy was diagnosed with painless parotid gland enlargement. He had pancytopenia and significantly raised serum lactate dehydrogenase. Fine-needle aspiration cytology from the parotid was suggestive of lymphoid malignancy. Flow cytometry and bone marrow biopsy suggested B-cell acute lymphoblastic leukemia. 18F-FDG PET/CT revealed extensive bone marrow disease and the involvement of the spleen, pancreas, kidneys, and the parotid, submandibular, and lacrimal glands. He had negligible physiological brain uptake.Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.