救助式前列腺切除术（sRP）历史上与高发病率相关联，但近期公布的多中心系列研究表明其结果有所改善。因此，我们按照系统性评价和荟萃分析的首选报告项目标准进行了系统性评估，以调查sRP的肿瘤学和功能结果以及发病率。我们包括了20篇回顾性文章，涵盖了4175名男性。机器人手术在40％的男性中执行，神经保留在36％的男性中使用。术后连续性在40.4％的患者中保持，勃起功能在＜16％的患者中保持。6.6％的患者描述了高级并发症（直肠损伤0.9％）。最终sRP病理显示，手术切缘阳性率为26.1％，32.8％的患者有精囊侵犯，并且国际泌尿病理学协会的等级大于3的患者占26.6％。10年无转移生存率范围为72％至77％，5年癌特异性生存率范围为86.6％至97.7％。救助式前列腺切除术表现出持久的肿瘤学控制，而发病率在近几年有所改善，尽管与原始前列腺切除术相比仍然显著。患者摘要：救助式前列腺切除术（sRP）的肿瘤学控制和发病率随时间不断改善。sRP的并发症及其功能结果似乎是可接受的，并且持续改善。版权所有©2023 European Association of Urology。Elsevier B.V.出版。保留所有权利。

Salvage radical prostatectomy (sRP) has historically been associated with high morbidity, whilst recently published multicentre series suggested a trend towards improved outcomes. Hence, we performed a systematic review according to the Preferred Reporting Items for Systematic Reviews and Meta-analyses criteria to investigate the oncological and functional results and morbidity of sRP. We included 20 retrospective articles comprising 4175 men. Robotic procedures were performed in 40% and nerve sparing in up to 36% of men. Postoperative continence was preserved in 40.4% of patients and erectile function in <16%. High-grade complications were described in 6.6% of patients (rectal injuries 0.9%). At final sRP pathology, surgical margins were positive in 26.1%, 32.8% had seminal vesicle invasion, and International Society of Urological Pathology grade was >3 in 26.6%. Ten-year metastasis-free survival ranged from 72% to 77% and 5-yr cancer-specific survival ranged from 86.6% to 97.7%. Salvage radical prostatectomy shows durable oncological control and morbidity improved over recent years, despite remaining significant compared to and higher than that of primary radical prostatectomy. PATIENT SUMMARY: Salvage radical prostatectomy (sRP) shows improving oncological control and morbidity over time. The complications associated with sRP and its functional results seem to be acceptable and are continuously improving.Copyright © 2023 European Association of Urology. Published by Elsevier B.V. All rights reserved.