患有癌症的患者常常会低估他们的抑郁症状，这会给患者和家人带来巨大的痛苦。本研究旨在确定在接受放射治疗的泰国癌症患者中，抑郁症状的普遍性和相关因素。研究结果可以促进和优化癌症患者的生活质量。本横断面研究调查了浅水湾医院的癌症门诊患者，调查时间为 2022 年 5 月至 7 月。问卷调查包括：（1）人口和个人数据，（2）病人健康问卷-9（PHQ-9）泰文版，（3）口头数字评级标度（VNRS），和（4）生活意义问卷（MLQ）。采用描述性统计方法分析了患者的人口统计学和抑郁症状，并报告了比例、频率、中位数和四分位距（IQR）。采用多元逻辑回归分析了自变量与抑郁症状的关联，并由 R Foundation for Statistical Computing 版本 4.1.2 进行了处理。所有置信区间（CIs）均在双侧 95％ 的水平上计算。本研究共有 113 名泰国癌症门诊患者参加。他们中的大多数为女性（61.1％），总体平均年龄为 56.2 ± 13.6 岁。参与者的癌症分期为 2 期和 3 期（分别为 31.0％ 和 32.7％）。没有任何参与者经历过重度抑郁症（PHQ-9 分数大于等于 9 分），并且所有参与者都是轻度（23.0％）或未出现/轻微抑郁症状（77.0％）。54 名参与者（47.8％）没有疼痛，其中一半（50.4％）有失眠症状。他们大多数在生活意义的各个子部分得分较高。与轻度抑郁症状相关的因素是住院史、个人健康感知、身体症状和疼痛。在本研究中，接受放射治疗的所有癌症参与者都没有重度抑郁症，大多数在生活中具有意义；然而，超过一半的人仍然经历疼痛和失眠症状。为了优化生活质量并预防抑郁症、身体症状和疼痛，应确保他们接受足够的治疗。此外，应促进感到生活有意义和对自身健康感满意的情感表达。 © 2023. The Author(s).

Depression in patients with cancer is frequently underestimated and causes major suffering to patients and families. This study purposed to determine the prevalence of, and factors associated with, depressive symptoms among Thai patients with cancer receiving radiotherapy. The results could promote and optimize the quality of life for patients with cancer.A cross-sectional study explored outpatients with cancer at Songklanagarind Hospital; from May to July 2022. The questionnaires inquired about: (1) demographic and personal data, (2) The Patient Health Questionnaire-9 (PHQ-9) Thai version, (3) Verbal Numerical Rating Scale (VNRS), and (4) The meaning in life questionnaire (MLQ). Patient demographics and depressive symptoms were analyzed using the descriptive statistic method and reported as: proportion, frequency, median and interquartile range (IQR). The analysis of the association between independent variables and depressive symptoms was conducted using multiple logistic regression, and performed by R Foundation for Statistical Computing version 4.1.2. All confidence intervals (CIs) were calculated at the 2-sided, 95% level.There were 113 Thai outpatients with cancer who participated in this study. The majority of them were female (61.1%), and the overall mean age was 56.2 ± 13.6 years. The participants' cancer staging was stage 2 and 3 (31.0%, and 32.7%, respectively). No participants had experienced major depression (PHQ-9 score of nine or greater), and all of them were mild (23.0%) or no/minimal depression (77.0%). Fifty-four participants (47.8%) were free of pain, with half of them (50.4%) having insomnia. Most of them had a high score in all subparts of meaning in life. The factors associated with mild depression were the history of hospitalization, the perception of one's health, the presence of physical symptoms, and pain.In this study, all cancer participants who received radiotherapy had either no/minimal or mild depression. No participants had major depression. Most participants had meaning in their life; however, over half of them still experienced pain and insomnia. To optimize the quality of life, and prevent depression, physical symptoms, and pain should ensure they receive adequate management. Additionally, feeling meaningful in life, and satisfaction in one's health should also be promoted.© 2023. The Author(s).