目的：本研究旨在分析和确定在沙特阿拉伯被诊断为Behçet病的患者的临床特征和特点。 方法：这项单中心研究在沙特阿拉伯西部地区的一家三级医疗中心进行。受过专业培训的风湿学家回顾了14岁及以上的BD患者的电子病历，并收集了他们的人口统计和临床数据。在比较之间，采用Fisher精确检验、独立t检验或Mann-Whitney U检验。使用Kolmogorov-Smirnov和Shapiro-Wilk检验检测变量的正态性。 结果：症状发生的平均年龄为29.6±11.4岁，诊断时的平均年龄为31.1±11.9岁。大多数患者超重（平均体质指数26.7±5.60 kg/m2）。最常见的医疗合并症是糖尿病和高血压。最常见的临床表现是口腔溃疡（91.2%）、生殖器溃疡（81.3%）、关节炎（41.8%）和伪滤泡炎（34.1%）。可考西林是最常用的治疗方法（95.6%），其次是泼尼松（72.5%）和硫唑嘌呤（36.3%）。男性患者更有可能患伪滤泡炎（p=0.011），并接受肿瘤坏死因子α（TNF-α）抑制剂治疗（p=0.045）。女性患者更有可能出现神经系统受累（p=0.029）。 结论：了解BD的症状和早期识别可以帮助提供及时有效的治疗，以避免疾病并发症。版权所有 © 2023，Alharthy等人。

Objective This study aimed to analyze and determine the clinical features and characteristics of patients diagnosed with Behçet's disease (BD) in Saudi Arabia. Methods This single-center study was conducted in a tertiary care center in the western region of Saudi Arabia. Electronic medical records of patients with BD aged 14 years and older were reviewed and their demographic and clinical data were collected by trained rheumatologists. Between comparisons, Fisher's exact test, independent t-test, or Mann-Whitney U test was applied. The normality of variables was tested using the Kolmogorov-Smirnov and Shapiro-Wilk tests. Results The mean age of symptom onset was 29.6 ± 11.4 years, and mean age at the time of diagnosis was 31.1 ± 11.9 years. Most patients were overweight (mean body mass index 26.7 ± 5.60 kg/m2). The most associated medical comorbidities were diabetes mellitus and hypertension. The most common clinical manifestations were oral ulcers (91.2%), genital ulcers (81.3%), arthritis (41.8%), and pseudofolliculitis (34.1%). Colchicine was the most prescribed treatment (95.6%), followed by prednisolone (72.5%), and azathioprine (36.3%). Male patients were significantly more likely to have pseudofolliculitis (p=0.011) and take a tumor necrosis factor alpha (TNF-α) inhibitor (p=0.045). Female patients were more likely to have neurological involvement (p=0.029). Conclusion Awareness of BD symptoms and early recognition can help provide timely and effective treatment to avoid disease complications.Copyright © 2023, Alharthy et al.