一位42岁的男性患者患有高危前列腺腺癌，进行了基线99m Tc-亚甲基二膦酸骨骼闪烁显像检查，发现两处骨转移和左股骨干处有微弱的放射性示踪物吸收区。鉴于病灶在骨扫描中仅为少量转移，患者年龄较小，是一位适合进行转移定向治疗的病人。为进一步确认该病变，进行了单光子发射计算机断层扫描（SPECT/CT）。结果显示为骨髓密度内的小软组织密度病变，暗示骨髓有受累。在高危前列腺癌患者中，可能需要对微弱放射性示踪物吸收区进行更敏感的评估，这种情况下，当先进技术受限时，这些症状的意义也需要重新评估。本文作者已发表于Thieme，依据知识共享署名许可证发布的开放获取文章，可在原文被正确引用时自由使用、分发和复制。( https://creativecommons.org/licenses/by/4.0/ )

A 42-year-old male patient with high-risk prostate adenocarcinoma underwent baseline 99m Tc-methylene diphosphonate skeletal scintigraphy, which revealed two skeletal metastases and an area of faint radiotracer uptake in the left femoral shaft. In view of oligo-metastatic nature of the disease in the bone scan and the young age of the patient, he was a candidate for metastases-directed treatment. Single photon emission computed tomography (SPECT)/CT was performed to further characterize this lesion. It was revealed to be a small soft tissue density lesion within the fatty bone marrow density, suggesting bone marrow involvement. A more sensitive evaluation of such areas with faint radiotracer uptake may be needed in high-risk prostate cancer patients where access to advanced modalities is limited. Their significance will also need reassessment as their detection will improve with technological advancements.The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. ( https://creativecommons.org/licenses/by/4.0/ ).