乳腺癌是可预防的，但却是全球最普遍的癌症之一。虽然定期筛查和监测已经导致发病率下降，但该恶性疾病依然会导致全球死亡率上升。由于传统癌症治疗方法的非特异性和侵略性特点，因此急需更好的治疗方法。纳米技术的最新进展已经在利用纳米载体进行靶向药物输送方面发挥了作用。优化过的纳米颗粒已被用于增加传统治疗药物的循环时间和靶向疗效。被动靶向包括表面调节，以避免药物通过标准身体防御系统而被排出体外。主动靶向则包括化学作用，可以针对癌症发展过程中过度表达的各种基因、受体和抗原。因此，本综述回顾了药物输送方法和基于纳米颗粒的靶向技术，这些技术有可能克服传统药物治疗的局限性。版权所有© Bentham Science Publishers；如有任何疑问，请发送电子邮件至epub@benthamscience.net。

Breast cancer is avertible yet one of the most widespread carcinomas globally. Though periodic screening and monitoring have resulted in reduced incidences, the malignancy claims increased death rates across the globe. Due to the non-specific and aggressive nature of available conventional cancer therapeutics, there is a crucial need for better treatment paradigms. Recent advancements in nanotechnology have aided in this by utilizing nanocarriers in targeted drug delivery approaches. Optimized nanoparticles have been used to enhance the circulation time and target the efficacy of conventional therapeutic drugs. Passive targeting comprises surface modulation to avoid drug elimination via a standard body defense system. Active targeting includes chemical interaction with various genes, receptors, and antigens overexpressed during cancer progression. Therefore, the present review recapitulates drug delivery approaches and nanoparticle-based targeting that can potentially overcome the limitations of conventional drug therapies.Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.