多个国家组织建议癌症护理提供者和肿瘤医学实践应对性别少数群体（SGM）患者的需求。肿瘤医学实践已经通过以SGM为重点的文化谦卑培训干预来尝试整合这一建议。如何最好地适应和实施此类培训在不同实践中尚不清楚。本文概述了一种将The Fenway Institute广泛使用的SGM培训适应到使用FRAME模型的肿瘤学环境的过程。 我们在两个肿瘤护理环境中进行了培训：一个乳腺肿瘤中心和一个放射肿瘤科。随后，我们对参与将The Fenway Institute的培训适应到这两个实践中的三名培训师进行了深入访谈。两名独立的调查员使用FRAME模型的组成部分作为分析指南对访谈进行编码。 培训团队成员描述了FRAME适应是如何主动和反应性地发生的；涉及SGM-identified训练师和来自实践中的防护者的多样背景的重要性；适应培训的背景和内容使其与肿瘤学听众相关；以及在整个过程中如何保持忠实于改善SGM患者健康护理核心原则的方法。 肿瘤提供者和职员的SGM文化谦卑培训必须经过迭代适应，以解决特定实践环境的政治和社会背景，并倡导更广泛的机构文化变革，以实现对SGM健康需求的响应。 版权所有©2022 Kamen、Reichelt、Dadgostar、Alpert、Doucette、Vaughan、Keuroghlian和Yousefi-Nooraie。

Multiple national organizations recommend that cancer care providers and oncology practices be responsive to the needs of sexual and gender minority (SGM) patients. Oncology practices have attempted to incorporate this recommendation through SGM-focused cultural humility training interventions. It is unclear how best to adapt and implement such training across practices. This manuscript outlines one process for adapting a widely-used SGM training from The Fenway Institute to the context of oncology settings using the Framework for Reporting Adaptations and Modifications-Enhanced (FRAME) model.We conducted training sessions in two oncology care settings: a breast oncology center and a radiation oncology department. Subsequently, we conducted in-depth interviews with the three trainers involved in adapting The Fenway Institute's training to these two practices. Two independent investigators coded the interviews using components of the FRAME model as an analytic guide.Training team members described the mechanisms by which FRAME adaption occurred both proactively and reactively; the importance of involving SGM-identified trainers of diverse backgrounds as well as champions from within oncology practices in which trainings were conducted; the importance of adapting both the context and content of training to be relevant to oncology audiences; and the ways in which fidelity to the core principles of improving health care for SGM patients was maintained throughout the process.SGM cultural humility training for oncology providers and staff must undergo iterative adaptation to address the political and social context of specific practice environments and advocate for broader institutional culture change to achieve responsiveness to SGM health needs.Copyright © 2022 Kamen, Reichelt, Dadgostar, Alpert, Doucette, Vaughan, Keuroghlian and Yousefi-Nooraie.