研究动态
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前列腺癌患者性健康护理指南:国际小组建议。

Guidelines for Sexual Health Care for Prostate Cancer Patients: Recommendations of an International Panel.

发表日期:2022 Nov 01
作者: Daniela Wittmann, Akanksha Mehta, Eilis McCaughan, Martha Faraday, Ashley Duby, Andrew Matthew, Luca Incrocci, Arthur Burnett, Christian J Nelson, Stacy Elliott, Bridget F Koontz, Sharon L Bober, Deborah McLeod, Paolo Capogrosso, Tet Yap, Celestia Higano, Stacy Loeb, Emily Capellari, Michael Glodé, Heather Goltz, Doug Howell, Michael Kirby, Nelson Bennett, Landon Trost, Phillip Odiyo Ouma, Run Wang, Carolyn Salter, Ted A Skolarus, John McPhail, Susan McPhail, Jan Brandon, Laurel L Northouse, Kellie Paich, Craig E Pollack, Jen Shifferd, Kim Erickson, John P Mulhall
来源: Best Pract Res Cl Ob

摘要:

翻译:在治疗后,患有前列腺癌的患者会遭受重大的性功能障碍,这会对他们和他们的伴侣产生负面影响,并影响他们的心理状态和关系。我们召集了一个国际小组,旨在制定指南,以告知临床医生、患者和伴侣有关前列腺癌治疗对患者和伴侣的性健康、关系以及前列腺癌康复中的生物心理社会方面的影响。指南小组包括国际专家研究人员和临床医生,以及指南方法学家。根据Cochrane干预系统性评述手册的指南,使用Ovid MEDLINE、Scopus、CINAHL、PsychINFO、LGBT Life和Embase数据库进行了系统文献综述(1995-2022)。根据系统综述和荟萃分析(PRISMA)指南进行研究选择。每个陈述都根据效益/风险评估分配了证据强度(A-C)和推荐级别(强、中、有条件)。数据综合包括对足够质量的研究(3个)进行荟萃分析,使用评估系统性综述的测量工具(AMSTAR)。基于可用证据和国际小组的专业知识,制定了关于前列腺癌患者的性健康护理指南。该指南考虑了患者的文化、种族和种族多样性。它们关注性取向和性别认同多样的个体的独特需求。该指南基于文献综述、前列腺癌治疗后性康复的理论模型和6个原则,旨在通过生物心理社会康复来促进临床医生对现实性成果和性副作用的减轻进行讨论。除了有关生活方式修改、评估、提供者教育和在前列腺癌康复中提供性健康护理的系统性挑战声明外,共有47个声明涉及心理性、关系和功能领域。该指南为临床医生提供了一个全面的前列腺癌患者的性健康护理方法。该研究的优势在于对前列腺癌性功能障碍和康复现有证据的全面评估,这可以与可用的专家知识一起为临床实践提供最佳支持。不足之处在于支持干预的证据的变化以及在低收入和中等收入国家面临的前列腺癌患者问题的研究不足。该指南记录了PCT的令人痛苦的性后遗症,提供了基于证据的性康复建议,并概述了未来研究的领域。©2022年,国际性医学学会。由Elsevier Inc.出版。保留所有权利。
Patients with prostate cancer suffer significant sexual dysfunction after treatment which negatively affects them and their partners psychologically, and strain their relationships.We convened an international panel with the aim of developing guidelines that will inform clinicians, patients and partners about the impact of prostate cancer therapies (PCT) on patients' and partners' sexual health, their relationships, and about biopsychosocial rehabilitation in prostate cancer (PC) survivorship.The guidelines panel included international expert researchers and clinicians, and a guideline methodologist. A systematic review of the literature, using the Ovid MEDLINE, Scopus, CINAHL, PsychINFO, LGBT Life, and Embase databases was conducted (1995-2022) according to the Cochrane Handbook for Systematic Reviews of Interventions. Study selection was based on Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Each statement was assigned an evidence strength (A-C) and a recommendation level (strong, moderate, conditional) based on benefit/risk assessment. Data synthesis included meta-analyses of studies deemed of sufficient quality (3), using A Measurement Tool to Assess Systematic Reviews (AMSTAR).Guidelines for sexual health care for patients with prostate cancer were developed, based on available evidence and the expertise of the international panel.The guidelines account for patients' cultural, ethnic, and racial diversity. They attend to the unique needs of individuals with diverse sexual orientations and gender identities. The guidelines are based on literature review, a theoretical model of sexual recovery after PCT, and 6 principles that promote clinician-initiated discussion of realistic expectations of sexual outcomes and mitigation of sexual side-effects through biopsychosocial rehabilitation. Forty-seven statements address the psychosexual, relationship, and functional domains in addition to statements on lifestyle modification, assessment, provider education, and systemic challenges to providing sexual health care in PC survivorship.The guidelines provide clinicians with a comprehensive approach to sexual health care for patients with prostate cancer.The strength of the study is the comprehensive evaluation of existing evidence on sexual dysfunction and rehabilitation in prostate cancer that can, along with available expert knowledge, best undergird clinical practice. Limitation is the variation in the evidence supporting interventions and the lack of research on issues facing patients with prostate cancer in low and middle-income countries.The guidelines document the distressing sexual sequelae of PCT, provide evidence-based recommendations for sexual rehabilitation and outline areas for future research.© 2022, International Society for Sexual Medicine. Published by Elsevier Inc. All rights reserved.