子宫颈癌是全球女性第四大常见癌症。我们旨在评估西非八个国家女性子宫颈癌风险因素的负担。我们使用2020年民生调查计划中八个西非国家（贝宁、喀麦隆、冈比亚、几内亚、利比里亚、马里、尼日利亚和塞拉利昂）的全国代表性样本的横断面数据。访谈员协助的调查评估了八个子宫颈癌风险因素（吸烟、早婚、体重指数、孕产次数、早孕、激素避孕药使用时间、多性伴侣和性传播感染）。数据使用描述性统计和泊松回归进行分析。民生调查计划对受访者的隐私和保密有伦理审查文件。我们从民生调查计划仓库获得使用数据的授权。共有128,173名年龄在15-49岁的妇女参与。利比里亚风险因素最多（平均3.05，SD 1.19），贝宁最少（平均2.20，SD 1.14）。冈比亚的平均初次性行为年龄最高，为18.15岁（95% CI 17.98-18.32），利比里亚最低，为15.72岁（15.62-15.81）。同样，冈比亚的平均初生年龄最高，为19.83岁（19.66-20.00），利比里亚最低，为18.69岁（18.54-18.83）。除了马里（45.9%）外，超过50％的妇女至少有两个孩子。在所有国家中，初次性行为年龄、初生年龄和孕产次数是最常见的风险因素。不同年龄组与风险因素数量显著相关。利比里亚30-34岁的妇女在所有国家中的IRR最高，为30%（1.18-1.42；p＜0.001）。冈比亚和尼日利亚受教育水平最高的妇女风险降低。研究限制包括来自不同年份的国家数据收集以及缺乏人类乳头状瘤病毒状态数据收集。将初次性行为年龄、初生年龄和孕产次数确定为子宫颈癌最常见的风险因素，将支持更有针对性的公共卫生干预（例如人类乳头状瘤病毒疫苗接种和子宫颈筛查）在数据收集的国家以及全球实施。 尼日利亚联邦政府。版权所有©2022 Elsevier Ltd。保留所有权利。

Cervical cancer is the fourth most common cancer in women worldwide. We aimed to assess the burden of cervical cancer risk factors among women in eight west African countries.Cross-sectional data from nationally representative samples of eight west African countries (Benin, Cameroon, Gambia, Guinea, Liberia, Mali, Nigeria, and Sierra Leone) as part of the demographic and health survey 2017-2020 were used. The interviewer-assisted survey assessed eight cervical cancer risk factors (smoking, early coitus, body-mass index, parity, early pregnancy, length of hormonal contraceptive use, multiple sexual partners, and sexually-transmitted infections). Data were analysed using descriptive statistics and Poisson regression. The Demographic and Health Service programme has ethical review documentation on the privacy and confidentiality of the respondents. We received authorisation to use the data from the Demographic and Health Service repository.A total of 128 173 women aged 15-49 years participated. Liberia had the highest number of risk factors (mean 3·05; SD 1·19), and Benin had the lowest (mean 2·20; SD 1·14). The mean age of first sexual intercourse was highest in Gambia at 18·15 years (95% CI 17·98-18·32) and lowest in Liberia at 15·72 years (15·62-15·81). Similarly, the highest mean age of first birth was 19·83 years (19·66-20·00) in Gambia, and the lowest is in Liberia at 18·69 years (18·54-18·83). Aside from Mali (45·9%), more than 50·0% of the women had at least two children. Age of first sexual intercourse, age of first birth, and parity were the most frequent risk factors across all the countries. Different age groups were significantly associated with the number of risk factors. Liberian women aged 30-34 years had the highest IRR of 30% (1·18-1·42; p<0·001) among all the countries. Women with the highest education level in Gambia and Nigeria had reduced risk. Limitations of the study included data collection from countries on different years and no human papillomavirus status data collection.Identification of age of first sexual intercourse, age of first birth, and parity as the most frequent risk factors of cervical cancer will support more focused public health interventions (such as human papillomavirus vaccination and cervical screening) in the countries that the data was collected from, as well as globally.Federal Government of Nigeria.Copyright © 2022 Elsevier Ltd. All rights reserved.