骨转移在膀胱癌（BC）患者中预后不良。本研究旨在构建预测骨转移性膀胱癌（BMBC）患者总体生存率的预后评分表。使用监测、流行病学和最终结果数据库招募了2010年至2018年间的BMBC患者。进行单变量和多变量分析来筛选预后因素并构建预后评分表。使用Harrell协调指数、受试者工作特征曲线和校准曲线来验证预后评分表。所有统计分析和图表制作均使用SPSS 23.0和R软件4.1.2。在监测、流行病学和最终结果数据库中确定了1361名BMBC患者。确定了六个独立的预后因素，包括婚姻状况、组织学类型、T分期、其他转移、手术和化疗，并将其纳入预后评分表的构建中。其中，化疗对评分表中的预后贡献最大。预后评分表的一致性指数在训练组和验证组中分别为0.745和0.753，所有曲线下面积的值均>0.77。校准曲线显示观察值与预测生存率之间完全一致。本研究开发的预后评分表预期将成为预测BMBC患者总体生存率的准确和个体化工具，并为适当的治疗或护理提供指导。版权所有 © 2023作者。 Wolters Kluwer Health，Inc.发表。

Bone metastasis has a poor prognosis in patients with bladder cancer (BC). This study aimed to construct a prognostic nomogram for predicting the overall survival of patients with bone-metastatic BC (BMBC). The Surveillance, Epidemiology, and End Results database was used to recruit patients with BMBC between 2010 and 2018. Univariate and multivariate analyses were performed to screen for prognostic factors and construct a nomogram. Harrell concordance index, receiver operating characteristic curve, and calibration curve were used to verify the prognostic nomograms. All statistical analyses and chart formation were performed using SPSS 23.0 and R software 4.1.2. A total of 1361 patients diagnosed with BMBC were identified in the Surveillance, Epidemiology, and End Results database. Six independent prognostic factors, including marital status, histological type, T stage, other metastases, surgery, and chemotherapy, were identified and included in the nomogram construction. Among them, chemotherapy contributed the most to the prognosis in the nomogram. The concordance index of the nomogram was 0.745 and 0.753 in the training and validation groups, respectively, and all values of the area under the curve were >0.77. The calibration curves showed perfect consistency between the observed and predicted survival rates. The prognostic nomogram developed in this study is expected to become an accurate and individualized tool for predicting overall survival in patients with BMBC and providing guidance for appropriate treatment or care.Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc.