COVID-19感染仍然在全世界范围内产生影响，也是一种重要的死亡原因。由感染导致的死亡率在1-5％之间变化，心血管风险因素尤其是高血压病例的死亡率更高。一些研究表明，血尿素氮（BUN）和白蛋白水平与COVID-19患者的预后不良有关。在我们的研究中，我们旨在调查BUN /白蛋白（BAR）比率是否对高血压COVID-19患者的住院死亡率产生影响。本研究共纳入800例高血压COVID-19患者，其中618例存活，182例死亡。排除了有心力衰竭、恶性肿瘤、急性冠状动脉综合征和心肌炎症状的患者。研究人群的中位年龄为69岁（60-77岁IQR），其中305名（38％）患者为男性。随访期间死亡的患者和存活患者在共病方面除慢性阻塞性肺疾病（COPD）外没有显着统计学差异，存活组的COPD显着较低（p = 0.014）。多元逻辑回归分析表明，年龄[OR：1.04，CI（1.01-1.06）；p = 0.002]、男性[OR：1.85，CI（1.13-3.02）; p = 0.010]、淋巴细胞计数[OR：0.63，CI（0.40-0.98）; p = 0.038] 、SaO2 [OR：0.82，CI（0.79-0.85）; p <0.001] 和BAR水平[OR：1.09，CI（1.04-1.16）；p = 0.001]是住院死亡的独立预测因子，ROC分析表明，BAR相对于单独使用白蛋白和BUN更能预测住院死亡。BUN、白蛋白和BAR水平被发现是COVID-19患者住院死亡的可靠预测因子，而BAR也被证明是比BUN和白蛋白水平更可靠的预测因子。高血压是COVID-19患病和死亡的主要风险因素之一，BAR提供了高血压COVID-19患者额外的预后数据，这可能会引导医生进行更加强制性的治疗。

The impact of COVID-19 infection still continues all over the world and is an important cause of mortality. The mortality rate due to infection varies between 1-5%. The mortality rate is higher in those with cardiovascular risk factors, especially in cases with hypertension. Some studies have shown that blood urea nitrogen (BUN) and albumin levels are associated with worse prognosis in patients with COVID-19. In our study, we aimed to investigate whether the BUN/albumin (BAR) ratio has an effect on in-hospital mortality in hypertensive COVID-19 patients.A total of 800 hypertensive COVID-19 patients, (618 of whom were alive and 182 died) were included in our study. Patients with a history of heart failure, malignancy, acute coronary syndrome, and myocarditis were excluded.The median age of the study population was 69 (60-77 IQR) years, and 305 (38%) of these patients were men. There was no statistically significant difference between the patients who died during follow-up and cases that remained alive in terms of comorbidities except chronic obstructive pulmonary disease (COPD) which was significantly lower in surviving group (p=0.014). Multivariable logistic regression analysis revealed that age [OR: 1.04, CI (1.01-1.06); p=0.002], male gender [OR: 1.85, CI (1.13-3.02); p=0.010], lymphocyte count [OR: 0.63, CI (0.40-0.98); p=0.038], SaO2 [OR: 0.82, CI (0.79-0.85); p<0.001] and BAR level [OR: 1.09, CI (1.04-1.16); p=0.001] were independent predictors of in-hospital mortality. ROC analysis yielded that BAR is a better predictor of in-hospital mortality compared to albumin and BUN alone.BUN, albumin, and BAR levels were found to be reliable predictors of in-hospital mortality in COVID-19 patients, and BAR was also found to be a more reliable predictor than BUN and albumin levels. Hypertension is one of the major risk factors for morbidity and mortality in COVID-19 and, BAR presents additional prognostic data in hypertensive COVID-19 patients that may direct physicians for treatment intensification.