海buckthorn（沙棘）是全球作为食品和健康保健品食用的，具有丰富的营养和药用价值。自古以来，人们在传统的中草药中使用海buckthorn不同部位，以缓解咳嗽、帮助消化、活血化瘀和减轻疼痛。植物化学研究揭示了海buckthorn中广泛的植物营养素，包括营养成分（蛋白质、矿物质、维生素等）和功能性成分，如黄酮类物质（1-99），木脂素（100-143），挥发油（144-207），单宁（208-230），萜类化合物（231- 260），固醇（261-270），有机酸（271-297）和生物碱（298-305）。药理学研究表明，海buckthorn的某些粗提取物或化合物具有各种健康益处，如抗炎，抗氧化，肝保护，抗心血管疾病，抗癌，降血糖，降血脂，神经保护，抗细菌活性，并且本文总结和分析了它们的有效剂量和实验模型。根据植物通俗进化，传统药用特性，扩展功效，药动学和代谢，以及组分可测试性，分析并预测了海buckthorn的质量标记（Q-标记）。本文还总结了海buckthorn在果汁，葡萄酒，油脂，发酵和酸奶中的应用，并对未来的展望进行了研究。然而，一些活性化合物的机制和结构-活性关系尚不清楚，质量控制和潜在毒性值得进一步研究。

Hippophae rhamnoides L. (sea buckthorn), consumed as a food and health supplement worldwide, has rich nutritional and medicinal properties. Different parts of H. rhamnoides L. were used in traditional Chinese medicines for relieving cough, aiding digestion, invigorating blood circulation, and alleviating pain since ancient times. Phytochemical studies revealed a wide variety of phytonutrients, including nutritional components (proteins, minerals, vitamins, etc.) and functional components like flavonoids (1-99), lignans (100-143), volatile oils (144-207), tannins (208-230), terpenoids (231-260), steroids (261-270), organic acids (271-297), and alkaloids (298-305). The pharmacological studies revealed that some crude extracts or compounds of H. rhamnoides L. demonstrated various health benefits, such as anti-inflammatory, antioxidant, hepatoprotective, anticardiovascular disease, anticancer, hypoglycemic, hypolipidemic, neuroprotective, antibacterial activities, and their effective doses and experimental models were summarized and analyzed in this paper. The quality markers (Q-markers) of H. rhamnoides L. were predicted and analyzed based on protobotanical phylogeny, traditional medicinal properties, expanded efficacy, pharmacokinetics and metabolism, and component testability. The applications of H. rhamnoides L. in juice, wine, oil, ferment, and yogurt were also summarized and future prospects were examined in this review. However, the mechanism and structure-activity relationship of some active compounds are not clear, and quality control and potential toxicity are worth further study in the future.