SPECT/CT是一种强大的工具，用于评估因具有钠碘共运输体（NIS）表达器官的良性摄取而导致的放射性碘意外浓度。我们报告了一种甲状腺乳头状癌放射性碘治疗后131碘在泪囊/导管中积聚的情况。在给予5.5 GBq的131碘后，3天后拍摄了全身扫描。SPECT/CT图像定位了泪囊/导管的局部示踪剂摄取，这很可能是由于先前放射性碘或碘治疗引起的泪道阻塞。混合SPECT/CT可以精确地解剖定位，并帮助区分良性模拟疾病，这可以改变患者的管理。

SPECT/CT is a powerful tool for assessing unexpected concentrations of radioiodine resulting from benign uptake in organs with sodium-iodide symporter (NIS) expression. We report a case of accumulation of 131Iodine in the nasolacrimal sac/duct after radioiodine therapy for papillary thyroid cancer. A whole-body scan was taken 3 days after the administration of 5.5 GBq of 131Iodine. SPECT/CT images localized the focal tracer uptake in the nasolacrimal sac/duct likely due to nasolacrimal duct obstruction secondary to prior radioiodine or iodine therapies. Hybrid SPECT/CT allows precise anatomical localization and help differentiate benign mimics of disease, which can alter patient management.