阿片类物质使用障碍(OUD)是一个重大的公共卫生问题，使用阿片类药物的个体死亡率比不使用此类药物的个体高出多达30倍。社会风险因素影响个体做出健康选择的能力，并对康复阿片类使用障碍的个体构成挑战。本研究旨在探讨已被开具阿片类药物处方的患者感染OUD的社会风险因素之间的关系。该回顾性队列研究的数据来自医疗保健系统的综合数据仓库，包括带有社会健康决策因素筛查信息、医疗和处方索赔数据的电子健康记录(EHR)。该研究比较了18岁或以上、被视为阿片类药物使用者的患者和EHR中有OUD诊断记录的患者的SDoH筛查结果。所有患者都接受了SDoH筛查。分析采用SAS统计分析系统(SAS Institute Inc, Cary, NC)进行。研究包括了2017年1月1日至2018年12月31日期间在医疗保健系统的初级护理或肿瘤学设施接受门诊服务的患者。有5003名阿片类药物使用者被视为使用阿片类药物，209名患者有阿片类药物的处方以及OUD的诊断记录。与阿片类使用组相比，患有OUD的患者更有可能教育程度较低、面临财务困难或粮食不安全。女性、40岁以上、以及高Charlson共病指数分数的患者与阿片类药物误用率较低相关。识别社会风险因素并为有OUD的个体提供适当的服务对于缓解康复挑战并促进这些个体整体健康至关重要。版权所有©2023美国药剂师协会®。由Elsevier Inc.出版。保留所有权利。

Opioid Use Disorder (OUD) is a major public health concern, with mortality rates in individuals who use opioid medications being up to 30 times greater than those of individuals who do not use such medications. Social risk factors influence one's ability to make healthy choices and pose challenges for individuals recovering from OUD.This study aimed to explore the relationship between OUD and social risk factors for patients who have been prescribed opioid medications.Data for this retrospective cohort study were obtained from a healthcare system's comprehensive data warehouses consisting of electronic health records (EHR) with Social Determinants of Health (SDoH) screening information, and medical and prescription claims data. The study compared patients 18 years of age or older with an opioid prescription who were considered users of opioids to patients who had a documented diagnosis of OUD in the EHR. All patients were screened for SDoH. The analyses were performed using Statistical Analysis System (SAS) (SAS Institute Inc, Cary, NC).The study included patients with an outpatient visit at one of the health care system's primary care or oncology facilities between January 1, 2017 and December 31, 2018. There were 5003 patients with an opioid prescription who were considered users of opioids, and 209 patients with an opioid prescription as well as a diagnosis of OUD. Compared to the opioid use group, patients with OUD were more likely to have a lower educational attainment, encounter financial hardship, or be food insecure. Being female, older than 40, and having a higher Charlson Comorbidity Index score were factors associated with lower rates of opioid misuse.Identifying social risk factors and providing appropriate services to individuals with OUD is essential in mitigating challenges to recovery and promoting overall health for these individuals.Copyright © 2023 American Pharmacists Association®. Published by Elsevier Inc. All rights reserved.