这是管理第3期非小细胞肺癌(NSCLC)的指南的简明语言摘要，也称为NSCLC。该指南是由美国临床肿瘤学会(ASCO)撰写并发表在《临床肿瘤学杂志》上。ASCO指南的目的是向美国的医疗专业人士包括肿瘤学家、外科医生、病理学家、放射科医生和护士提供关于NSCLC患者的最佳诊断和治疗建议。ASCO指南基于最新研究和科学证据，确保推荐是最新的，基于可靠的数据和最佳实践。2021年，ASCO请一组专家形成专家小组。专家小组审查了127项关于NSCLC的临床研究结果，这些研究在1990年至2021年之间进行。他们研究了这些研究中NSCLC的诊断和治疗方式，以及患者的生存和生活质量。专家小组使用这些发现和自己的专业知识形成了他们的建议，并制定了2021年ASCO指南，称为“NSCLC第3期的管理：ASCO指南”。指南旨在回答以下问题：在怀疑患有第3期疾病的人中，确认和分期NSCLC的最精确的方式是什么？哪些患有第3期NSCLC的患者可以通过手术最成功地治疗？哪些患者可以在手术前进行额外的治疗？哪些可以进行手术治疗的患者可以在手术后进行额外治疗？哪种治疗和/或管理适合不能手术治疗的患者？

This is a plain language summary of a guideline on the management of stage 3 non-small-cell lung cancer, also known as NSCLC. This guideline was written by the American Society for Clinical Oncology (ASCO for short) and published in the Journal of Clinical Oncology.The purpose of the ASCO guideline is to provide recommendations to healthcare professionals in the US including oncologists, surgeons, pathologists, radiologists, and nurses on how best to diagnose and treat people with stage 3 NSCLC.The ASCO guideline is based on the latest research and scientific evidence to make certain the recommendations are up to date and based on reliable data and best practice. In 2021, a group of experts were asked by ASCO to form an Expert Panel. The Expert Panel reviewed the results of 127 clinical research studies on NSCLC that were done between 1990 and 2021. They looked at how NSCLC had been diagnosed and treated in these studies, as well as at patients' survival and quality of life. The Expert Panel used these findings and their own expertise to form their recommendations and produce the 2021 ASCO Guideline called 'Management of Stage 3 Non-Small-Cell Lung Cancer: ASCO Guideline'.The guideline aims to answer the following questions: What are the most precise ways to confirm and stage NSCLC in people suspected of having a stage 3 disease? Which patients with stage 3 NSCLC can be treated most successfully with surgery? Which patients who can be treated with surgery could also have an additional therapy before their surgery? Which patients who can be treated with surgery could also have an additional treatment after their surgery? Which treatment and/or management is most suitable for patients who cannot have surgery?