GI因素,在放疗过程中预测前列腺运动的潜力:一项范围性综述。
GI factors, potential to predict prostate motion during radiotherapy; a scoping review.
发表日期:2023 May
作者:
S E Alexander, U Oelfke, H A McNair, A C Tree
来源:
DIABETES OBESITY & METABOLISM
摘要:
进行了范围文献回顾以确定在放射治疗期间最有可能影响前列腺运动的胃肠(GI)因素。我们认为,对这些GI因素进行患者特定的测量可以预测放射治疗期间的运动不确定性,通过优化治疗技术(例如每日适应或通过量身定制的患者预备和准备),实现个性化治疗。范围回顾根据JBI指南进行。在四个数据库(Ovid Medline®,EMBASE,CINAHL和EBSCO discovery)中进行了搜索。包括2010年至今的英语文章。不包括有关儿科、仅限生物女性、传染性和治疗后GI病变和饮食的文章。确定了影响男性的常见GI因素及相关症状、发生率和测量工具。探讨了前列腺癌患者中的患病率并讨论了适当的评估工具。初步搜索确定了四个突出的GI因素:心理健康、共病和药物、体育活动和盆底障碍。范围搜索发现了3644篇文章;排除了1646篇重复的文章。经过标题和摘要筛选后又排除了1249篇文章,剩下162篇全文审阅:42篇心理健康、53篇共病和药物、39篇体育活动和28篇盆底障碍。确定了前列腺癌人群中普遍存在的六个GI因素,并估计其最有可能影响前列腺运动:抑郁症、焦虑、糖尿病、肥胖、体育活动不足和盆底障碍。有可靠、快速、易于使用的工具可量化这些因素。创建了一套全面的GI因素评估方案,适合实施到放射治疗诊所中。提前揭示这些GI因素将指导放射治疗的改进个性化。©2023作者。
A scoping literature review was conducted to identify gastrointestinal (GI) factors most likely to influence prostate motion during radiotherapy. We proffer that patient specific measurement of these GI factors could predict motion uncertainty during radiotherapy, facilitating personalised care by optimising treatment technique e.g., daily adaption or via bespoke patient pre-habilitation and preparation.The scoping review was undertaken as per JBI guidelines. Searches were conducted across four databases: Ovid Medline®, EMBASE, CINAHL and EBSCO discovery. Articles written in English from 2010-present were included. Those pertaining to paediatrics, biological women exclusively, infectious and post-treatment GI morbidity and diet were excluded.Common GI factors impacting men were identified and related symptoms, incidence and measurement tools examined. Prevalence among persons with prostate cancer was explored and suitable assessment tools discussed.A preliminary search identified four prominent GI-factors: mental health, co-morbidity and medication, physical activity, and pelvic floor disorder. The scoping search found 3644 articles; 1646 were removed as duplicates. A further 1249 were excluded after title and abstract screening, 162 remained subsequent to full text review: 42 mental health, 53 co-morbidity and medication, 39 physical activity and 28 pelvic floor disorder.Six GI factors prevalent in the prostate cancer population and estimated most likely to influence prostate motion were identified: depression, anxiety, diabetes, obesity, low physical activity, and pelvic floor disorder. Reliable, quick, and easy to use tools are available to quantify these factors.A comprehensive GI factor assessment package suitable to implement into the radiotherapy clinic has been created. Unveiling these GI factors upfront will guide improved personalisation of radiotherapy.© 2023 The Authors.