本研究旨在通过对经过椭圆孔切除术（TL）、中颅窝切除术（MF）或枕骨后切除术（RS）的患者尸体颞骨中耳闻小骨化（CO）模式进行调查。尸体颞骨的组织病理学分析。搜索国家耳聋和沟通障碍研究所、加州大学洛杉矶分校House耳研究所和马萨诸塞州眼耳病理实验室的颞骨系列中有VS病史并进行了显微手术的尸体颞骨。排除标准包括非VS和手术后30天内死亡的患者。对基底、中间和顶部环进行组织学分析以评估CO。从两个数据库中共有92个有肿瘤病史的颞骨中，有12例符合纳入标准。肿瘤切除方式包括2例MF、4例RS和6例TL切口。所有进行了TL手术的颞骨中，都观察到了CO。在进行MF或RS手术的颞骨中，有5/6没有CO，1/6仅部分骨化。在进行组织病理学和病历回顾后，这一单例发现在RS手术后有前庭侵犯。在这个颞骨系列中，所有进行了TL手术的颞骨都通过组织学分析展示了不同程度的CO。MF和RS的案例中除了前庭侵犯的病人外，都没有表现出CO。所以当计划或可能在VS手术后进行人工耳蜗移植时，医生可能应考虑采用不违反迷路的手术方法。© 2023 American Academy of Otolaryngology-Head and Neck Surgery Foundation。

This study aims to investigate patterns of cochlear ossification (CO) in cadaveric temporal bones of patients who underwent vestibular schwannoma (VS) surgery via the translabyrinthine (TL), middle cranial fossa (MF), or retrosigmoid (RS) approaches.Histopathologic analysis of cadaveric temporal bones.Multi-institutional national temporal bone repository.The National Institute of Deafness and Communication Disorders and House Temporal Bone Laboratory at the University of California, Los Angeles and the Massachusetts Eye and Ear Otopathology Laboratory were searched for cadaveric temporal bones with a history of VS for which microsurgery was performed. Exclusion criteria included non-VS and perioperative death within 30 days of surgery. Temporal bones were analyzed histologically for CO of the basal, middle, and apical turns.Of 92 temporal bones with a history of schwannoma from both databases, 12 of these cases met the inclusion criteria. The approaches for tumor excision included 2 MF, 4 RS, and 6 TL approaches. CO was observed in all temporal bones that had undergone TL surgery. Among temporal bones that had undergone MF or RS surgeries, 5/6 had no CO, and 1/6 had partial ossification. This single case was noted to have intraoperative vestibular violation after RS surgery upon histopathologic and chart review.In this temporal bone series, all temporal bones that had undergone TL demonstrated varying degrees of CO on histological analysis. MF and RS cases did not exhibit CO except in the case of vestibular violation. When cochlear implantation is planned or possible after VS surgery, surgeons may consider using a surgical approach that does not violate the labyrinth.© 2023 American Academy of Otolaryngology-Head and Neck Surgery Foundation.