我们的目标是描述澳大利亚农村癌症幸存者的身体活动（PA）、肥胖和生活质量（QoL），评估总体和项目特定的QoL是否与足够的PA和肥胖有关，以及评估PA和肥胖在QoL方面是否存在互动。在一项横断面研究中，采用方便抽样方法，通过澳大利亚鲍鲍夏自治区的一个农村医院的化疗日单元和联合卫生专业人员招募成年癌症幸存者。排除标准是急性营养不良和临终关怀。使用Godin-Shephard和7项癌症治疗功能评估（FACT-G7）问卷评估PA和QoL。通过线性回归和逻辑回归分别评估与总体和项目特定QoL相关的因素。在103名农村癌症幸存者中，中位年龄为66岁，35%足够身体活动，41%肥胖。 FACT-G7评估中，平均/中位数总QoL得分为17分（0-28分；得分越高表示生活质量越好）。足够的PA与更好的QoL（[公式：见文] = 2.29；95%置信区间[CI] = 0.26，4.33）和更多的能量（比值比[OR] = 4.00，95% CI = 1.48，10.78）有关，而肥胖与更差的QoL（[公式：见文] = -2.09；95% CI = -4.17，-0.01）和更多的疼痛（OR = 3.88，95% CI = 1.29，11.68）有关。 PA-肥胖交互作用无显著性（p值= 0.83）。这是已知的首项针对任何癌症幸存者进行的农村幸存者研究，发现足够的PA和肥胖分别与更好和更差的QoL有关。在针对和调整农村癌症幸存者的支持性护理干预时，应考虑PA、体重管理和QoL - 包括能量和疼痛。 （2023年。作者（s）。）

We aimed to describe physical activity (PA), obesity, and quality of life (QoL) among rural Australian cancer survivors, assess whether total and item-specific QoL are associated with sufficient PA and obesity, and assess whether PA and obesity interact with respect to QoL.In a cross-sectional study, convenience sampling was used to recruit adult cancer survivors via a chemotherapy day unit and allied health professionals at a rural hospital in Baw Baw Shire, Australia. Exclusion criteria were acute malnutrition and end-of-life care. PA and QoL were measured using Godin-Shephard and 7-item Functional Assessment of Cancer Therapy (FACT-G7) questionnaires, respectively. Factors associated with total and item-specific QoL were assessed via linear and logistic regression, respectively.Among 103 rural cancer survivors, the median age was 66 years, 35% were sufficiently physically active, and 41% presented with obesity. Mean/median total QoL scores were 17 on the FACT-G7 scale (0-28; higher scores indicate better QoL). Sufficient PA was associated with better QoL ([Formula: see text]=2.29; 95% confidence interval [CI] = 0.26, 4.33) and more energy (odds ratio [OR] = 4.00, 95% CI = 1.48, 10.78) while obesity was associated with worse QoL ([Formula: see text]=-2.09; 95% CI = -4.17, -0.01) and more pain (OR = 3.88, 95% CI = 1.29, 11.68). The PA-obesity interaction was non-significant (p-value = 0.83).This is the first known study conducted among rural survivors of any cancer to find sufficient PA and obesity are associated with better and worse QoL, respectively. PA, weight management, and QoL-including energy and pain-should be considered when targeting and tailoring supportive care interventions for rural cancer survivors.© 2023. The Author(s).