动态免疫标记作为不良反应（irAEs）生物标志物。
Dynamic immune signatures as biomarkers for irAEs.
发表日期：2023 Mar 18
作者：
Jingwen Yang, Yamei Chen, Leng Han
来源：
Epigenetics & Chromatin
摘要：
鉴定免疫相关不良事件(irAEs)的预测性生物标志物对于最大化免疫检查点抑制剂(ICIs)治疗癌症患者的效益至关重要。在最近发表于Med的一项研究中，Nuñez等人利用多组学方法，识别出有潜力预测自身免疫毒性发展的血液免疫特征。版权所有©2023 Elsevier Inc.。保留所有权利。
Identifying predictive biomarkers of immune-related adverse events (irAEs) is crucial to maximize the benefits for patients with cancer treated with immune checkpoint inhibitors (ICIs). In a recent study published in Med,Nuñez et al. utilized multi-omics approaches and identified blood immune signatures that have the potential to predict the development of autoimmune toxicity.Copyright © 2023 Elsevier Inc. All rights reserved.