构建一个全面的健康老龄评分（HAS），探讨其与全因死亡的关联以及与其他人口统计学因素在死亡上的潜在相互作用。本研究包括来自中国健康和养老纵向调查的5,409名年龄≥60岁的参与者。基于三个健康老龄维度，包括内在能力（IC）、环境支持（ES）和慢性疾病（CD），在基线评估后构建了HAS，并按照三分位数进行分类（差、中等和优）。从2011年到2018年，每两年进行一次全因死亡的随访，通过死亡登记或家庭采访进行。使用Cox回归、拉普拉斯回归和接收器操作特征分析对数据进行分析。 在7年的随访中，有877名（16.21%）参与者死亡。HAS基于IC维度中的认知、机动性和日常生活活动能力，ES维度中的住房以及CD维度中的高血压、糖尿病、慢性肺病、中风和癌症进行构建，该评分与死亡有关联。HAS似乎是全因死亡的良好预测因子，其曲线下面积为0.749。与高HAS相比，中等和差HAS与全因死亡的危险比和95%置信区间分别为1.26（1.01-1.56）和2.38（1.94-2.91）。与拥有高HAS的参与者相比，拥有差HAS的参与者的中位生存时间缩短了2.46年。 HAS与年龄、性别和婚姻状况在死亡方面具有显著的加性交互作用。 差HAS可能会增加死亡率并缩短生存期，尤其是在老年、男性和单身成年人中。©作者（S）2023年。由牛津大学出版社代表美国老年学学会出版。 Note: The translation is in simplified Chinese.

To construct a comprehensive healthy aging score (HAS) and explore its association with all-cause mortality and its potential interactions with other demographics on mortality.This study included 5,409 participants aged ≥60 years from the China Health and Retirement Longitudinal Study. An HAS was constructed based on three dimensions of healthy aging including intrinsic capacity (IC), environmental support (ES), and chronic disease (CD), which were assessed at baseline, and categorized by tertiles (poor, moderate, and high). Participants were followed up biennially for all-cause mortality through the death registration or family interview from 2011 to 2018. Data were analyzed using Cox regression, Laplace regression, and receiver-operating characteristic analysis.During 7 years of follow-up, 877 (16.21%) participants died. An HAS was constructed based on the cognition, mobility, and instrumental activity of daily living in the IC dimension; housing in the ES dimension; and hypertension, diabetes, chronic lung disease, stroke, and cancer in the CD dimension, which was associated with death. HAS seems a good predictor of all-cause mortality, with an area under the curve of 0.749. The hazard ratios and 95% confidence intervals for all-cause mortality related to moderate and poor HAS (vs high HAS) were 1.26 (1.01-1.56) and 2.38 (1.94-2.91), respectively. The median survival time was 2.46 years shorter in participants with poor HAS than those with high HAS. There were significant additive interactions of HAS with age, sex, and marital status on death.Poor HAS may increase mortality and shorten survival, especially among older, male, and single adults.© The Author(s) 2023. Published by Oxford University Press on behalf of The Gerontological Society of America.