接受化疗的患者面临营养不良和高症状负担的风险，营养干预可以改善临床和支持性护理。本研究确定了在化疗期间遵循地中海饮食干预的障碍和促进因素。癌症患者（任何类型）接受化疗的参与了一项临床试验，测试8周地中海饮食干预对癌症相关疲劳的影响。参与者被随机分组为2：1，地中海饮食干预组：对照组。干预包括食品提供、教育、食谱、与营养师的会话和每周跟进。干预后，所有参与者都完成了半结构化的离组访谈。访谈被转录并进行开放性编码，以描述遵循地中海饮食干预的促进因素和障碍。参与者（n=29，干预组n=21）的年龄为51.0±15.1岁，93.1％有乳腺癌。教育材料和方便的食品提供是最常报告的促进因素。许多患者认为改变饮食给予了控制和增强的感觉。障碍包括冷冻食品口感不佳，参与者（或他们的配偶/子女）的食品偏好与地中海饮食不符，化疗引起的副作用阻止了食物的消化（例如口腔溃疡，食欲不振）。这个项目有助于了解营养干预对患者的影响，以优化化疗期间的饮食计划。

Patients undergoing chemotherapy are at risk for malnutrition and a high symptom burden, and nutritional interventions can address clinical and supportive care outcomes. Herein, we identified barriers and facilitators to adhering to a Mediterranean Diet (MedDiet) intervention during chemotherapy. Patients with cancer (any type) who were undergoing chemotherapy were enrolled into a clinical trial testing the effects of an 8-week MedDiet intervention on cancer-related fatigue. Participants were randomized 2:1, MedDiet:control. The intervention entailed food provision, education, a cookbook, a session with a nutritionist, and weekly check-ins. Post-intervention, all participants completed semi-structured exit interviews. The interviews were transcribed and open coding was conducted to describe the facilitators and barriers to MedDiet adherence. Participants (n = 29, n = 21 in the intervention group) were 51.0 ± 15.1 years old and 93.1% had breast cancer. Educational materials and convenient food delivery were the highest reported facilitators. Many patients offered that changing their diet gave a sense of control and empowerment. Barriers to adherence were that the frozen food was unappetizing, participants' (or their spouse/children's) food preferences did not align with the MedDiet, and chemotherapy-induced side effects that prevented food consumption (eg, mouth sores, lack of appetite). This project helps understand the patient experience within nutritional interventions to optimize dietary programs during chemotherapy treatment.