用于无药物抗血管新生和光热治疗肿瘤的人类VEGF磁性分子印迹聚合物。
A human VEGF magnetic molecularly imprinted polymer for drug-free anti-angiogenesis and photothermal therapy of tumors.
发表日期：2023 Mar 21
作者：
Mengzhao Wen, Haizhu Shi, Yu Wan, Jiateng Wu, Xiao Tian, Qian Chen, Ming-Yu Wu, Shun Feng
来源：
Cellular & Molecular Immunology
摘要：
一种磁性分子印迹聚合物是通过表位印迹技术以人类VEGF表位肽作为模板开发的。作为一种无药物的代理，纳米粒子可以通过整合抗血管生成和光热治疗的方式显著抑制肿瘤细胞的增殖。这项工作提供了一个成功的多模式抗癌药物设计的示例。
A magnetic molecularly imprinted polymer was developed with an epitope peptide of human VEGF as a template via an epitope blotting technique. As a drug-free agent, the nanoparticles can significantly suppress the proliferation of tumor cells by integrating anti-angiogenesis and photothermotherapy. This work provides a successful example of the design of multimodal antineoplastic drugs.