该研究的目的是探索全身磁共振成像（MRI）在评估原发性骨肉瘤分期中的肺外转移扮演的角色。我们回顾性地审查医疗数据，以确定已进行分期或再分期的原发性骨肉瘤患者是否有可用的术前全身MRI。如果有病理组织学结果，则将其作为诊断性能的参照测试。否则，将肿瘤科委员会的决定用作参照。此外，还研究了全身MRI与F-氟脱氧葡萄糖正电子发射计算机断层摄影（18F-FDG PET-CT）和骨显像的优势。 总共有36名骨肉瘤患者（24名分期，12名再分期），平均年龄为16.36±5.63岁（范围为9-29岁），并包括在研究中。中位随访时间为26.61个月（四分位距33.3个月）。在36名患者中，8名骨骼转移，1名淋巴结转移，1名皮下转移。全身MRI正确识别了所有转移性疾病患者，但错误地将一名患者的骨梗死分类为骨骼转移，导致扫描水平的灵敏度、特异度、准确性、阴性预测价值和阳性预测价值均为100％、96.3％、97.3％、100％和90.91％。全身MRI通过识别一名患者的骨骼转移，为骨显像做出了贡献，并通过排除另一名患者的骨骼转移，为正电子发射计算机断层摄影做出了贡献。 全身MRI可准确识别原发性骨肉瘤患者的肺外转移，用于分期或再分期。此外，它可能对标准的全身成像方法做出贡献。版权所有©2023 Wolters Kluwer Health, Inc.保留所有权利。

The aim of the study is to investigate the role of whole-body magnetic resonance imaging (MRI) in assessing extrapulmonary metastases in primary osteosarcoma staging.We retrospectively reviewed medical data to identify primary osteosarcoma patients with available preoperative whole-body MRI obtained in the staging or restaging. Histopathology was the reference test for assessing the diagnostic performance, if available. Otherwise, oncology board decisions were used as the reference. In addition, the benefits of whole-body MRI to F-fluorodeoxyglucose positron emission tomography-computed tomography (18F-FDG PET-CT) and bone scintigraphy were investigated.In all, 36 patients with osteosarcoma (24 staging, 12 restaging) with a mean age of 16.36 ± 5.63 years (range, 9-29 years) were included in the study. The median follow-up duration was 26.61 months (interquartile range, 33.3 months). Of 36 patients, 8 had skeletal, 1 had a lymph node, and 1 had a subcutaneous metastasis. Whole-body MRI correctly identified all patients with metastatic disease but incorrectly classified a bone infarct in one patient as a skeletal metastasis, equating a scan-level sensitivity, specificity, accuracy, negative predictive value, and positive predictive value of 100%, 96.3%, 97.3%, 100%, and 90.91%. Whole-body MRI contributed to bone scintigraphy by identifying a skeletal metastasis in one patient and positron emission tomography-computed tomography by ruling out a skeletal metastasis in another.Whole-body MRI could accurately identify extrapulmonary metastases in primary osteosarcoma patients for staging or restaging. In addition, it might contribute to the standard whole-body imaging methods.Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.