儿童癌症幸存者报告的晚期影响、寻求生存护理的动机和出席模式。
Childhood Cancer Survivors' Reported Late Effects, Motivations for Seeking Survivorship Care, and Patterns of Attendance.
发表日期:2023 Mar 21
作者:
Christina Signorelli, Claire E Wakefield, Jordana K McLoone, Karen A Johnston, Ann C Mertens, Michael Osborn, Richard J Cohn,
来源:
Brain Structure & Function
摘要:
童年癌症幸存者容易患上长期治疗相关的健康问题,这会导致生活质量下降。对于澳大利亚和新西兰长期幼儿癌症幸存者的整体健康或幸存者参加幸存者门诊的动因方面,缺乏一些数据。本研究向主要诊断≥5年的幸存者进行了横断面问卷调查。我们比较了不同癌症诊断的参与者报告的晚期影响数量,并确定了与晚期影响负担和参与癌症幸存者关怀相关的临床(如治疗)和人口统计学(如年龄)因素。共有634名参与者完成了问卷调查(48%男性,平均年龄为21.7岁)。大多数参与者(79%)报告了至少一个与癌症相关的晚期影响,最常见的是疲劳(40%)和记忆/学习障碍(34%)。与其他癌症诊断的幸存者相比,脑瘤幸存者报告的晚期影响总数更高(平均5.7比3.2,P<0.001)。参与关怀的最常见动因是了解他们因癌症和/或治疗可能在后期出现的问题(98.5%)和获取有关健康状况的保证(97.4%)。在不同癌症诊断组中,支持每种动因的幸存者比例相似,唯一的例外是更多地了解保险和养老金(脑瘤幸存者最高,达到80%)。在多变量分析中,幸存者更可能报告参与幸存者关怀,如果他们年龄较小(P<0.001),自诊断以来的时间较短(P<0.001),或他们报告的动因数量更高(P=0.016)。幸存者在治疗完成数十年后报告出现了一系列健康问题。了解晚期影响的负担和寻求幸存者关怀动因对于确保量身定制的干预或服务满足这一不断增长人群的需求,并设计有效的幸存者关怀模式至关重要。©作者(2023年)。由牛津大学出版社出版。
Childhood cancer survivors are vulnerable to long-term treatment-related health conditions, which can lead to poor quality of life. Little data exist on the overall health of long-term Australian and New Zealand childhood cancer survivors or on survivors' motivations for attending survivorship clinics.This study administers a cross-sectional questionnaire to long-term survivors ≥5 years from their primary diagnosis. We compared participant-reported number of late effects by a cancer diagnosis, and identified clinical (eg, treatment) and demographic (eg, age) factors that were associated with late effects burden and engagement in cancer survivorship care.A total of 634 participants completed questionnaires (48% male, mean age = 21.7 years). Most participants (79%) reported at least one cancer-related late effect, most commonly fatigue (40%) and memory/learning difficulties (34%). Brain tumor survivors reported a higher total number of late effects than survivors with other diagnoses (mean = 5.7 vs. 3.2, P < .001). Participants' most commonly reported motivators for engaging in care were to understand problems that may occur later in life because of their cancer and/or treatment (98.5%) and to get reassurance about one's health (97.4%). The proportion of survivors endorsing each motivating factor was similar across cancer diagnoses, with the exception of learning more about insurance and pensions (highest in brain tumor survivors = 80%). In multivariable analyses, survivors were more likely to report being engaged in survivorship care if they were younger (P < .001), less time had elapsed since their diagnosis (P < .001), or they reported a higher number of motivating factors (P = .016).Survivors report a range of health problems decades after treatment completion. Understanding the burden of late effects, and motivators for seeking survivorship care to manage these health problems, is important for ensuring that tailored interventions or services are available to meet the needs of this growing population and to design effective models of survivorship care.© The Author(s) 2023. Published by Oxford University Press.