(1) 背景：胰腺癌是第三大致死率的癌症，预测表明其在患病率中所占比例越来越大。治疗的基础是住院化疗，重点在于姑息治疗。 (2) 方法：基于快速综述方法在PubMed和Cochrane数据库中进行文献综述，搜索结果还包括雪球搜索的出版物。采用AMSTAR2修改方案对纳入的出版物进行定性评估。 (3) 结果：综述包括17篇出版物，其中大部分涉及与采用的治疗方案相关的直接成本。大多数出版物重点比较药物治疗的成本效益和姑息治疗的成本。其他出版物涉及由胰腺癌产生的间接成本。它们特别关注因病假而导致的失去生产力的经济负担。 (4) 结论：胰腺癌发病率的增加导致医疗保健系统和间接成本的增加。由于住院治疗在医疗结构中所占的重要份额，直接成本正在增加。住院治疗方案和副作用会导致胰腺癌患者失去生产力。在消化系统肿瘤中，胰腺癌产生的间接成本排名第二，尽管其发病率比占主导地位的结肠直肠癌低得多。这表明该癌症的经济负担是一个重要问题。

(1) Background: Pancreatic cancer is the cancer with the third-highest mortality rate, and forecasts indicate its growing share in morbidity. The basis of treatment is inpatient chemotherapy and there is a strong focus on palliative care. (2) Methods: A literature review was conducted based on the rapid review methodology in PubMed and Cochrane databases. The search was supplemented with publications from the snowball search. Qualitative assessment of included publications was performed using AMSTAR2 modified scheme. (3) Results: The review included 17 publications, of which majority concerned direct costs related to the adopted treatment regimen. Most of the publications focused on comparing the cost-effectiveness of drug therapies and the costs of palliative treatment. Other publications concerned indirect costs generated by pancreatic cancer. They particularly focused on the economic burden of lost productivity due to sickness absence. (4) Conclusion: The increase in the incidence of pancreatic cancer translates into an increase in the costs of the health care system and indirect costs. Due to the significant share of hospitalization in the health care structure, direct costs are increasing. The inpatient treatment regimen and side effects translate into a loss of productivity for patients with pancreatic cancer. Among gastrointestinal cancers, pancreatic cancer generates the second largest indirect costs, although it has a much lower incidence rate than the dominant colorectal cancer. This indicates a significant problem of the economic burden of this cancer.