癌症已成为发展中国家（包括埃塞俄比亚）的公共卫生问题和挑战。埃塞俄比亚阿姆哈拉地区缺乏关于癌症流行病学的本地数据。因此，本研究旨在描述前往菲莱格·希沃特转诊医院就诊的癌症患者的流行病学特征。本研究基于埃塞俄比亚阿姆哈拉区巴希尔达尔菲莱格·希沃特转诊医院的患者癌症登记。该医院是阿姆哈拉地区的主要转诊医院，服务超过500万人口。该医院设有肿瘤科等单位提供随访医疗服务。研究对象为在2017年7月至2019年6月期间前往肿瘤科单位接受治疗的所有已确认的癌症患者。使用全球莫兰I统计方法评估各地区癌症病例的空间异质性。执行Getis-Ord Gi*统计方法，以确定高癌症病例区域的热点区域。在两年时间内，一共有1888名已确认的癌症患者登记。癌症患者在女性（60.8％，95％CI 58.5至63.0％）和男性（39.3％，95％CI 37.0至41.5％）之间有显著差异。前三种最常见的癌症类型包括乳腺癌（19.4％）、宫颈癌（12.9％）和淋巴瘤（15.7％）。乳腺癌、宫颈癌和淋巴瘤在女性中是前三种最常见的癌症类型，而淋巴瘤、肉瘤和肺癌在男性中是前三种最常见的癌症。空间上，研究区域的癌症病例不是随机分布的（全球莫兰I = 0.25，z-score = 5.6，p值<0.001）。巴希尔达尔市政府（z = 3.93，p <0.001）、梅查（z = 3.49，p <0.001）、阿德特（z = 3.25，p <0.01）、阿切费尔（z = 3.29，p <0.001）、丹吉拉（z = 3.32，p <0.001）、佛各拉（z = 2.19，p <0.05）和德拉（z = 2.97，p <0.01）在空间上成为具有高病例集群的热点区域。我们发现，不同性别的癌症类型存在差异。本研究为深入研究与癌症相关的环境和职业暴露因素提供了见解，以指导未来的癌症预防和控制计划。本研究还呼吁扩大区域内包括农村地区在内的癌症登记站点。

Cancer has become a public health problem and a challenge in developing countries, including Ethiopia. There is scanty local data on cancer epidemiology in Amhara region, Ethiopia. Thus, this study aimed to describe epidemiological characteristics of cancer patients attending Felege Hiwot Referral Hospital.This study was based on a patient cancer registry that took place in Bahir Dar Felege Hiwot Referral Hospital, Amhara Regional State, Ethiopia. It is the main referral hospital in the Amhara region, and serves more than 5 million people. The hospital has units including oncology for follow-up health care services. All confirmed cancer patients attending oncology units from July 2017 to June 2019 were included in the study. Global Moran's I statistic was employed to assess spatial heterogeneity of cancer cases across districts. Getis-Ord Gi* statistics was performed to identify hot spot districts with high numbers of cancer cases.In a two-year period, a total of 1888 confirmed cancer patients were registered. There was a significant variation of cancer patients between females (60.8% 95%CI 58.5 to 63.0%) and males (39.3% 95%CI 37.0 to 41.5%). The first three most frequent cancer types seen were breast (19.4%) and cervical cancer (12.9%), and lymphoma (15.7%). Breast and cervical cancer and lymphoma were the first three cancers type among women, whereas lymphoma, sarcoma, and lung cancer were the three most common cancer among men. Spatially, cancer cases were non-random in the study area (global Moran's I = 0.25, z-score = 5.6, p-value < 0.001). Bahir Dar city administration (z = 3.93, p < 0.001), Mecha (z = 3.49, p < 0.001), Adet (z = 3.25, p < 0.01), Achefer (z = 3.29, p < 0.001), Dangila (z = 3.32, p < 0.001), Fogera (z = 2.19, p < 0.05), and Dera (z = 2.97, p < 0.01) were spatially clustered as hotspot with high numbers of cluster cases.We found that there is a variation in the cancer types with sex. This study provides an insight for further exploration of environmental and occupational exposure related factors for cancer to guide future cancer prevention and control programs. The current study also calls for expansion of cancer registry sites, including in rural areas in the region.