用于快速装配微流控器件的模块化元件必须额外努力解决各个模块之间泄漏和对准问题。我们展示了具有自愈性能的导电弹性体，并提出了一种新的模块化微流控器件配置系统，利用自愈性能替代传统的芯片形式而无需外部接口。具体来说，强健室温自愈弹性基体PP（聚氨酯/2-甲酰苯硼酸）的关键是由聚氨酯（PU）和2-甲酰苯硼酸（2-FPBA）之间建立的双动态共价键交联（亚胺和硼酸酯键）。通过原位金属还原获得的MXene和氧化石墨烯（GO）构成的稳定层间距（Al-O键）的MG（MXene/GO）导电网络赋予PP光热导电性。一步液态成型从PP和MGPP（MG/PP）中获得拼图形状的标准化模块化元件库。利用外泌体验证了构建的微流控电化学生物传感平台的性能。该设备具有广泛的检测范围（50-105颗/μL）和低检测限（42颗/μL）（S/N = 3），为结肠癌外泌体的定量检测提供了一种一次性、可重复使用、经济实用和快速分析平台。此外，据我们所知，这是关于自愈性导电弹性体用于模块化微流控电化学生物传感平台的第一次探索。

Modular components for rapid assembly of microfluidics must put extra effort into solving leakage and alignment problems between individual modules. Here, we demonstrate a conductive elastomer with self-healing properties and propose a modular microfluidic component configuration system that utilizes self-healing without needing external interfaces as an alternative to the traditional chip form. Specifically, dual dynamic covalent bond crosslinks (imine and borate ester bonds) established between Polyurethane (PU) and 2-Formylbenzeneboronic acid (2-FPBA) are the key to a hard room-temperature self-healing elastomeric substrate PP (PU/2-FPBA). An MG (MXene/GO) conductive network with stable layer spacing (Al-O bonds) obtained from MXene and graphene oxide (GO) by in situ reduction of metals confers photothermal conductivity to PP. One-step liquid molding obtained a standardized modular component library of puzzle shapes from PP and MGPP (MG/PP). The exosomes were used to validate the performance of the constructed microfluidic electrochemical biosensing platform. The device has a wide detection range (50-105 particles/μL) and a low limit of detection (LOD) (42 particles/μL) (S/N = 3), providing a disposable, reusable, cost-effective, and rapid analysis platform for quantitative detection of colorectal cancer exosomes. In addition, to our knowledge, this is the first exploration of self-healing conductive elastomers for a modular microfluidic electrochemical biosensing platform.