早期癌症检测作为一个重大的公共卫生问题具有重大意义。一种基于MoS2/C60复合纳米层的场效应晶体管（FET）用作通道材料，通过添加光源提高了设备性能，从而实现了癌症相关miRNA的超灵敏检测。在本研究中，采用原子层沉积（ALD）逐层沉积MoS2，C60则通过蒸发涂层器沉积，获得表面形态良好的复合纳米层作为FET的通道材料。基于C60对蓝紫光的良好吸收，选择405纳米激光照射通道材料，提高了FET生物传感器的功能。miRNA-155的超低检测限为5.16 aM，线性检测窗口从10 pM到1 fM。

As a major public health issue, early cancer detection is of great significance. A field-effect transistor (FET) based on an MoS2/C60 composite nanolayer as the channel material enhances device performance by adding a light source, allowing the ultrasensitive detection of cancer-related miRNA. In this work, atomic layer deposition (ALD) was used to deposit MoS2 layer by layer, and C60 was deposited by an evaporation coater to obtain a composite nanolayer with good surface morphology as the channel material of the FET. Based on the good absorption of C60 by blue-violet light, a 405 nm laser was selected to irradiate the channel material, improving the function of FET biosensors. A linear detection window from 10 pM to 1 fM with an ultralow detection limit of 5.16 aM for miRNA-155 was achieved.