研究动态
Articles below are published ahead of final publication in an issue. Please cite articles in the following format: authors, (year), title, journal, DOI.

碳点:癌症治疗中的机遇与挑战。

Carbon Dots: Opportunities and Challenges in Cancer Therapy.

发表日期:2023 Mar 22
作者: Tanima Bhattacharya, Gye Hwa Shin, Jun Tae Kim
来源: Pharmaceutics

摘要:

近年来,碳点(CDs)因其多种性质而受到广泛研究和报道。特别是碳点的特定特性被认为是一种可能的癌症诊断和治疗技术。这也是一种为治疗各种疾病带来新思路的尖端技术。尽管碳点还处于初级阶段,尚未向社会展示其价值,但其发现已经带来了一些值得注意的进展。CDs的应用表明自然成像的转化。利用CD进行摄影在生物成像、新药发现、靶向基因传递、生物传感、光动力疗法和诊断方面表现出非凡的适用性。本综述旨在提供对CDs的全面了解,包括它们的优点、特性、应用和作用方式。在这个概述中,将重点介绍许多CD设计策略。此外,我们还将讨论大量的细胞毒性测试研究,以证明CDs的安全性。本研究将介绍CDs的生产方法、机制、正在进行的研究以及在癌症诊断和治疗方面的应用。
Recently, carbon dots (CDs) have been actively studied and reported for their various properties. In particular, the specific characteristics of carbon dots have been considered as a possible technique for cancer diagnosis and therapy. This is also a cutting-edge technology that offers fresh ideas for treating various disorders. Though carbon dots are still in their infancy and have not yet shown their value to society, their discovery has already resulted in some noteworthy advancements. The application of CDs indicates conversion in natural imaging. Photography using CDs has demonstrated extraordinary appropriateness in bio-imaging, the discovery of novel drugs, the delivery of targeted genes, bio-sensing, photodynamic therapy, and diagnosis. This review seeks to provide a comprehensive understanding of CDs, including their benefits, characteristics, applications, and mode of action. In this overview, many CD design strategies will be highlighted. In addition, we will discuss numerous studies on cytotoxic testing to demonstrate the safety of CDs. The current study will address the production method, mechanism, ongoing research, and application of CDs in cancer diagnosis and therapy.