研究动态
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在小儿脑部肿瘤幸存者中,关于前额系统行为评分表的信息者评级与自我报告评级的一致性。

Concordance of informant and self-reported ratings on the Frontal Systems Behavior Scale in adult survivors of pediatric brain tumor.

发表日期:2023 Mar 29
作者: Olivia C Haller, Elizabeth L Tighe, Tricia Z King
来源: Brain Structure & Function

摘要:

有理论认为,小儿脑肿瘤幸存者可能对其执行功能有减少的洞察力。共同评估者和幸存者之间的一致性被用来探究这个理论,但结果并不一致。本研究旨在通过研究73名成年幸存者及其共同评估者在前额系统行为量表(FrSBe)评分和参与者角色之间的关系来扩展先前工作。本研究还旨在测试得分一致性是否因肿瘤治疗方式的不同而有所变化。对偶混合效应模型考察了参与者在FrSBe细分量表评分上的评估和参与者角色之间的关系。内类相关(ICC)用于计算可靠变化指数,以评估自我和评估者协议的显著差异。对偶混合效应模型显示,参与者角色与FrSBe冷漠和执行功能亚量表的评分之间不存在显著关系。参与者角色与FrSBe疏忽亚量表的评分有关。冷漠的ICC为ICC = .583,疏忽的ICC = .420,执行功能的ICC = .373。得分之间的显著差异并不因化学放射治疗历史而变化。结果表明,参与者角色对某个FrSBe细分量表存在影响,并且存活者和评估者分数之间存在弱至中等的一致性,这表明共同评估者和幸存者之间的一致性因FrSBe领域而异。存活者和评估者之间最强的关系出现在冷漠领域,这表明冷漠是幸存者和家人共同关心的问题。
It has been theorized that pediatric brain tumor survivors may have reduced insight into their executive functioning. Agreement between informants and survivors has been used to probe this theory, but findings have been inconsistent. This study sought to expand on prior work by examining the relationship between participant role and ratings on the Frontal Systems Behavior Scale (FrSBe) among 73 adult survivors and their informants. This study also sought to test whether agreement on scores varied as a function of tumor treatment.Dyadic mixed effects models examined the relationship between participant ratings on FrSBe subscales and the role of a participant (survivor or informant). Intraclass correlations (ICC) were used to calculate reliable change indices to evaluate significant divergence in self and informant agreement.Dyadic mixed effects models showed an insignificant relationship between participant role and ratings on the FrSBe apathy and executive dysfunction subscales. Participant role was related to ratings on the disinhibition subscale of the FrSBe. The ICC for apathy was ICC = .583, for disinhibition ICC = .420, and for executive dysfunction ICC = .373. Significant divergence in scores did not vary by history of chemoradiation.Results demonstrate an effect of role on one FrSBe subscale and weak to moderate agreement between survivor and informant scores, which suggests that agreement between informants and survivors varies by FrSBe domain. The strongest relationship between survivors and informants was seen on apathy, which suggests that apathy is a shared concern for survivors and their families.