由于其高的发病率和死亡率，黑色素瘤引起了广泛关注。传统的治疗方法仍存在一些问题和缺陷，因此越来越多的新颖方法和材料正在不断发展。银纳米颗粒（AgNPs）因其出色的抗氧化、抗增殖、抗炎、抗菌、抗真菌和抗肿瘤能力而在癌症研究领域特别是黑色素瘤治疗方面引起了极大的关注。本文主要介绍了 AgNPs 在预防、诊断和治疗皮肤黑色素瘤中的应用，并侧重于光动力疗法（PDT）、光热疗法（PTT）和化疗等黑色素瘤治疗的治疗策略。总的来说，AgNPs 在皮肤黑色素瘤治疗中扮演着越来越重要的角色，未来有着很有前途的应用。版权所有©2023 Elsevier B.V.出版。

Melanoma has remarkably gained extensive attention owing to its high morbidity and mortality. Conventional treatment methods still have some problems and defects. Therefore, more and more novel methods and materials have been continuously developed. Silver nanoparticles (AgNPs) have attracted significant interest in the field of cancer research especially for melanoma treatment because of their excellent properties including antioxidant, antiproliferative, anti-inflammatory, antibacterial, antifungal, and antitumor abilities. In this review, the applications of AgNPs in the prevention, diagnosis, and treatment of cutaneous melanoma are mainly introduced. It also focuses on the therapy strategies of photodynamic therapy (PDT), photothermal therapy (PTT), and chemotherapy for melanoma treatment. Taken together, AgNPs play an increasingly crucial role in cutaneous melanoma treatment, which have promising application in the future.Copyright © 2023. Published by Elsevier B.V.