肾上腺是多种原发肿瘤，包括肺癌、乳腺癌和黑色素瘤的常见转移部位。手术切除被认为是标准护理，但由于解剖位置和/或患者和/或疾病特征相关的挑战，手术并不总是可行的。立体定向体放射线治疗（SBRT）是治疗少量转移的一种有前途的方法，尽管有关肾上腺转移的文献仍然不一致。本文总结了SBRT治疗肾上腺转移瘤的最相关的已发布研究。初步数据表明，SBRT具有高局部控制率和轻微的毒性模式，并有助于减轻症状。应考虑使用先进的放疗技术，包括IMRT和VMAT，BED10 > 72 Gy以及使用4DCT进行运动控制，以获得高质量的肾上腺转移瘤消融治疗。版权所有©2022 Elsevier Inc.。

Adrenal glands represent a common site of metastases from several primary tumors, including lung cancer, breast cancer and melanoma. Surgical resection is considered the standard of care, but surgery is not always feasible given the challenges related to anatomical site and/or due to patient and/or disease characteristics. Stereotactic body radiation therapy (SBRT) represents a promising treatment for oligometastases, though the literature on its role for adrenal metastases is still heterogeneous. Herein are summarized the most relevant published studies on the efficacy and safety of SBRT for adrenal gland metastases. The preliminary data suggests that SBRT yields high local control rates and symptom relief with a mild pattern of toxicity. Advanced radiotherapy techniques including IMRT and VMAT, a BED10 > 72 Gy and the use of 4DCT for motion control should be considered for a high quality ablative treatment of adrenal gland metastases.Copyright © 2022 Elsevier Inc. All rights reserved.