为比较基于涡轮自旋回波（TSE）和回声计划成像（EPI）的IVIM成像在口腔癌患者中的图像质量、表观弥散系数（ADC）和IVIM衍生参数，并评估ADC和IVIM衍生参数的等效性，30名口腔癌患者接受了3.0T系统下的TSE-IVIM和EPI-IVIM成像。比较了两个序列之间的扭曲比（DR）、信噪比（SNR）、对比度噪声比（CNR）、图像质量的定性评估、ADC、纯弥散系数（D）、伪弥散系数（D*）和灌注分数（f）。使用Bland-Altman分析评估口腔癌定量参数在TSE和EPI序列之间的一致性。结果表明，TSE-IVIM的DR明显小于EPI-IVIM（P < 0.001）。EPI-IVIM的大部分解剖部位的CNR显著高于TSE-IVIM（P < 0.05），而SNR没有显著差异（P > 0.05）。与EPI-IVIM相比，TSE-IVIM具有更高的图像质量、更少的失真和伪影以及更低的图像对比度（P < 0.05）。尽管没有显著差异存在（P > 0.05），但EPI-IVIM的病变边缘锐度和诊断信心低于TSE-IVIM。TSE-IVIM的ADC和D具有更好的重复性（ICC > 0.9）。尽管在两个序列之间的病变的ADC和IVIM衍生参数没有显著差异（P > 0.05），但在Bland-Altman图中发现了较宽的协议限。因为比起EPI-IVIM，TSE-IVIM具有更好的图像质量，因此可以作为口腔癌患者的替代技术。此外，TSE-IVIM可以提供更准确的定量参数。然而，两个IVIM技术衍生的定量参数不能用于口腔癌患者的等效参数。

To compare the image quality, apparent diffusion coefficient (ADC), and intravoxel incoherent motion- (IVIM) derived parameters of IVIM imaging based on turbo spin-echo (TSE) and echo-planar imaging (EPI) of patients with oral cancer and to assess the equivalence of the ADC and IVIM-derived parameters.Thirty patients with oral cancer underwent TSE-IVIM and EPI-IVIM imaging using a 3.0-T system. The distortion ratio (DR), signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), qualitative evaluations of image quality, ADC, pure diffusion coefficient (D), pseudo-diffusion coefficient (D*), and perfusion fraction (f) were compared between the two sequences. The consistency of the quantitative parameters in oral cancer between the TSE and EPI sequences was evaluated using a Bland-Altman analysis.TSE-IVIM had a significantly smaller DR than EPI-IVIM (P < 0.001). The CNR of EPI-IVIM on most of the anatomical sites was significantly higher than that of TSE-IVIM (P < 0.05), while the SNR was not significantly different (P > 0.05). TSE-IVIM had significantly higher image quality, less distortion and artifacts, and lower image contrast compared with EPI-IVIM (P < 0.05). The lesion-edge sharpness and diagnostic confidence of EPI-IVIM were lower than that of TSE-IVIM, although no significant differences existed (P > 0.05). The ADC and D of TSE-IVIM had better reproducibility (intraclass correlation coefficient > 0.9). Although no significant difference existed for the ADC and IVIM-derived parameters of lesions between the two sequences (P > 0.05), wide limits of agreement were found in the Bland-Altman plots.TSE-IVIM could be used as an alternative technique to EPI-IVIM for patients with oral cancer because of its better image quality. Furthermore, TSE-IVIM can provide more accurate quantitative parameters. However, the quantitative parameters derived from the two IVIM techniques cannot be used as equivalent parameters for patients with oral cancer.