银屑病、特应性皮炎和脓性汗腺炎的十大研究优先事项:SkIN加拿大优先设定倡议。
Top Ten Research Priorities for Psoriasis, Atopic Dermatitis and Hidradenitis Suppurativa: The SkIN Canada Priority Setting Initiative.
发表日期:2023
作者:
Aaron M Drucker, Omer Kleiner, Rachael Manion, Anie Philip, Jan Dutz, Kathleen Barnard, Julie Fradette, Lucie Germain, Robert Gniadecki, Ivan Litvinov, Sarvesh Logsetty, Morris Manolson, P Régine Mydlarski, Vincent Piguet, Debbie Ward, Youwen Zhou, An-Wen Chan,
来源:
Burns & Trauma
摘要:
加拿大皮肤调查网络(SkIN Canada)是一项新的全国性皮肤研究网络。为塑造研究领域并确保其对患者护理具有价值,必须确定患者、护理人员和医疗保健提供者认为重要的研究优先事项。为了确定九种主要皮肤状况的前十位研究优先事项,我们首先进行了医疗保健提供者和研究人员的调查,选择未来在炎症性皮肤病、非黑色素瘤皮肤癌和伤口愈合类别中进行研究的前十位皮肤状况。对于这些被选出的皮肤状况,我们进行了范围性评估,以确定以前的优先事项设置练习。我们将那些范围性评论的结果与患者、医疗保健提供者和研究人员的调查结果进行了结合,为每个状况生成了知识空白列表。然后,我们进行了患者和医疗保健提供者的调查,以创建初步的排名,以确定那些知识空白的优先事项。最后,我们进行了患者和医疗保健提供者的研讨会,以创建每个状况的最终前十位研究优先事项列表。总体而言,至少有538名患者、医疗保健提供者和研究人员参加了至少一项调查或研讨会。银屑病、特应性皮炎和腋臭症(炎症性皮肤疾病);慢性伤口、烧伤和疤痕(伤口愈合);以及基底细胞、鳞状细胞和默克尔细胞癌(皮肤癌)被选为优先皮肤状况。针对炎症性皮肤疾病的知识空白的前十个列表涵盖了与患者护理相关的一系列问题,包括病因、预防、非药物和药物管理的问题。源自患者和医疗保健提供者的研究优先事项应该用于指导加拿大和国际上的多学科研究网络、资助机构和政策制定者。
The Skin Investigation Network of Canada (SkIN Canada) is a new national skin research network. To shape the research landscape and ensure its value to patient care, research priorities that are important to patients, caregivers, and health care providers must be identified.To identify the Top Ten research priorities for 9 key skin conditions.We first surveyed health care providers and researchers to select the top skin conditions for future research within the categories of inflammatory skin disease, skin cancers (other than melanoma), and wound healing. For those selected skin conditions, we conducted scoping reviews to identify previous priority setting exercises. We combined the results of those scoping reviews with a survey of patients, health care providers, and researchers to generate lists of knowledge gaps for each condition. We then surveyed patients and health care providers to create preliminary rankings to prioritize those knowledge gaps. Finally, we conducted workshops of patients and health care providers to create the final Top Ten lists of research priorities for each condition.Overall, 538 patients, health care providers, and researchers participated in at least one survey or workshop. Psoriasis, atopic dermatitis and hidradenitis suppurativa (inflammatory skin disease); chronic wounds, burns and scars (wound healing); and basal cell, squamous cell and Merkel cell carcinoma (skin cancer) were selected as priority skin conditions. Top Ten lists of knowledge gaps for inflammatory skin conditions encompassed a range of issues relevant to patient care, including questions on pathogenesis, prevention, non-pharmacologic and pharmacologic management.Research priorities derived from patients and health care providers should be used to guide multidisciplinary research networks, funders, and policymakers in Canada and internationally.