肝母细胞瘤是儿童肝源性最常见的原发恶性肿瘤，估计发病率为每百万儿童0.5-1.5例。肝母细胞瘤经典位置在肝实质内，而有蒂肝母细胞瘤是相对稀有的一种。由于其超肝位置和可能的细的有蒂部位在影像学中不易识别，因此准确诊断可能是具有挑战性的。本文报告了一个四个月大男婴左上腹可触及的巨大无症状肝母细胞瘤的病例，最初基于腹部超声发现疑似神经母细胞瘤。通过腹部CT扫描做出巨大有蒂肝母细胞瘤的最终诊断，并通过经皮活检确诊。由于肿瘤巨大，最初无法完全切除。因此，病人接受了数次化疗治疗。肿瘤缩小后完全切除。该病人已治愈，并在6个月随访中未发现并发症。有蒂肝母细胞瘤虽然罕见，但应在儿科患者的肝周围肿物中考虑，可能会被误诊为其他上腹部肿块，如肾上腺肿块。因此，在这种情况下，我们必须在影像学中寻找血管蒂，并记住AFP检查。©2023.本文作者。

Hepatoblastoma is the most common primary malignancy of hepatic origin in children, with an estimated incidence of 0.5-1.5 per million children. Hepatoblastoma classically has an intraparenchymal location, and pedunculated hepatoblastoma is a relatively rare entity. Accurate diagnosis can be challenging due to its extrahepatic location and possibly its thin peduncle, which is not easily identified in imaging.Here, we report a case of asymptomatic giant palpable hepatoblastoma in the LUQ of a four-month-old male infant, initially suspected of neuroblastoma based on abdominal ultrasound findings. The final diagnosis of giant pedunculated hepatoblastoma was made based on the abdominal CT scan and the diagnosis was confirmed by percutaneous biopsy. Due to the size of the tumor, complete removal of the tumor was not initially possible. Therefore, the patient was treated with several courses of chemotherapy. The tumor was shrunk and then completely removed. The patient was treated, and no complications were found in the 6-month follow-up.Pedunculated hepatoblastoma is rare but should be considered as a possibility in the case of a perihepatic mass in a pediatric patient that can be confused with other upper abdominal masses such as an adrenal mass. Therefore, in such cases, we must look for the vascular pedicle in the imaging and keep the AFP check in mind.© 2023. The Author(s).